“…Biochemical investigations employing non-radioactive dilution methods have been used to assess the body composition (Crooke & Morris, 1942;Cruickshank & Whitfield, 1945;Schwartz, Schachter & Freinkel, 1949;Courtice & Guntar, 1949;Edwards & White, 1960) but the results show variations according to the materials used. Thus although sucrose, inulin and thiosulphate may all be used to measure the extracellular fluid volume, the three results all vary to a significant extent because of differences in distribution (Ikkos, 1955).…”