The Determination of the Minimum Nitrogen Requirement of the Adult Dog for Maintenance of Nitrogen Balance

Kade, Charles F.; Phillips, Jean Houston; Phillips, William A.

doi:10.1093/jn/36.1.109

Cited by 13 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lower values reported here reflect the differences in methodology and objectives between this short-term study and previous studies used to inform the NRC guidelines. For example, previous studies investigated responses to methionine supplementation in low-protein diets (33)(34)(35)(36) and estimated total SAA as approximately 0•5-1 g/4184 kJ. One long-term study (15) found no adverse effects when beagles were fed a diet containing total SAA of 1•3 g/4184 kJ for 4 years.…”

Section: Discussionmentioning

confidence: 99%

Short-term determination and long-term evaluation of the dietary methionine requirement in adult dogs

Harrison¹,

Thomas²,

Gilham³

et al. 2020

Br J Nutr

View full text Add to dashboard Cite

Methionine, an essential sulphur-containing amino acid (SAA), plays an integral role in many metabolic processes. Evidence for the methionine requirements of adult dogs is limited, and we employed the indicator amino acid oxidation (IAAO) method to estimate dietary methionine requirements in Labrador retrievers (n 21). Using semi-purified diets, the mean requirement was 0·55 (95 % CI 0·41, 0·71) g/4184 kJ. In a subsequent parallel design study, three groups of adult Labrador retrievers (n 52) were fed semi-purified diets with 0·55 g/4184 kJ (test diet 1), 0·71 g/4184 kJ (test diet 2) or 1·37 g/4184 kJ (control diet) of methionine for 32 weeks to assess the long-term consequences of feeding. The total SAA content (2·68 g/4184 kJ) was maintained through dietary supplementation of cystine. Plasma methionine did not decrease in test group and increased significantly on test diet 1 in weeks 8 and 16 compared with control. Reducing dietary methionine did not have a significant effect on whole blood, plasma or urinary taurine or plasma N-terminal pro B-type natriuretic peptide. Significant effects in both test diets were observed for cholesterol, betaine and dimethylglycine. In conclusion, feeding methionine at the IAAO-estimated mean was sufficient to maintain plasma methionine over 32 weeks when total SAA was maintained. However, choline oxidation may have increased to support plasma methionine and have additional consequences for lipid metabolism. While the IAAO can be employed to assess essential amino acid requirements, such as methionine in the dog using semi-purified diets, further work is required to establish safe levels for commercial diet formats.

show abstract

Section: Discussionmentioning

confidence: 99%

Short-term determination and long-term evaluation of the dietary methionine requirement in adult dogs

Harrison¹,

Thomas²,

Gilham³

et al. 2020

Br J Nutr

View full text Add to dashboard Cite

show abstract

“…The composition of the original amino-acid mixture and the diet we used is given in Tables 2 and 3 (Hardy et al, 1977 and. In a series of studies in which we deleted, one at a time, each of the amino-acids known to be essential for the growing rat (Anon., 1978) we found that Greaves, 1965: Miller & Allison, 1958Greaves & Scott, 1960Kade et al, 1948Gessert & Phillips, 1956;Arnold & Schad, 1954: Payne, 1965 Anon. I98 1 a Anon.…”

Section: Introductionmentioning

confidence: 88%

Do cats really need more protein?

Rogers

Morris

1982

J of Small Animal Practice

View full text Add to dashboard Cite

Reviews of the most recent literature on amino‐acid and nitrogen requirements have shown that the minimal protein requirement (using a protein with a high NPU) of the growing kitten is about 20 per cent of the diet whether the requirement is based on the nitrogen content of the protein or upon its essential amino‐acid content. Although this is higher than that required by the growing dog, rat or man, the difference is not as great (65 per cent higher) as the differential found for adult animals of these same species. That is, the adult cat requires 12–15 per cent dietary protein for maintenance compared with about 4–5 per cent for the adult rat, man and dog.

show abstract

“…[13][14][15] The current National Research Council (NRC) recommends a minimum protein requirement of 80 g of crude protein per kg diet in foods with an energy density of 4.0 kilocalories (kcal) ME/g, when proteins that are of high quality (both bioavailable and with the correct amounts of the essential amino acids) are fed. However, differences in the protein sources, energy densities, and amino acid ratios of the experimental diets have led to a great deal of confusion regarding this requirement.…”

Section: Dogsmentioning

confidence: 99%

Protein Requirements

Case¹

2011

Canine and Feline Nutrition

View full text Add to dashboard Cite

The Determination of the Minimum Nitrogen Requirement of the Adult Dog for Maintenance of Nitrogen Balance

Cited by 13 publications

References 8 publications

Short-term determination and long-term evaluation of the dietary methionine requirement in adult dogs

Short-term determination and long-term evaluation of the dietary methionine requirement in adult dogs

Do cats really need more protein?

Protein Requirements

Contact Info

Product

Resources

About