The devastating effects of humeral nonunion on health-related quality of life

Brinker, Mark R.; Loftis, Christopher M.; Khoriaty, Justin D.; Dunn, Warren R.

doi:10.1016/j.jse.2022.05.012

Cited by 5 publications

(1 citation statement)

References 30 publications

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“…As a non-union remains untreated, pain, stiffness, reduced range of motion, and impaired function progress in tandem [16,17]. The exacerbation of these symptoms and their impact on patients' functioning and activities of daily living (ADLs) can place significant weight on their mental health and hinder quality of life [18].…”

Section: Introductionmentioning

confidence: 99%

Clinical, Radiologic, and Functional Outcomes following Bone Grafting for Metacarpal Non-Unions: A Systematic Review

El Sewify,

Abi-Rafeh,

Legler

et al. 2024

JCM

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Objectives: Metacarpal non-unions are complex hand defects that can lead to severe hand impairment. Treatment may require the use of artificial or autologous bone grafts. This systematic review aims to describe the outcomes of bone grafting following metacarpal non-union in an attempt to establish an optimal therapeutic protocol for this complication. Methods: A systematic review was conducted in adherence with PRISMA guidelines. Data collection and analysis were performed in duplicate and confirmed by a third investigator. Our primary outcomes focused on radiological time to bone fusion and rates of non-union. Additionally, functional outcomes and complications were analyzed as means of central tendency. Results: Eighteen studies were included in the systematic review, accounting for a total of 47 patients. The average follow-up time was 12.4 months. Fourteen studies analyzed radiological outcomes, with atrophic non-union representing the most common type. The time to bone fusion, assessed radiologically, following bone graft was an average of 6.9 months (n = 14), with a 100% rate of union in 42 patients. Regarding patient-reported pain improvement, 76% of patients experienced pain relief. Moreover, all patients reported a complete subjective return to baseline hand function. Adverse events, limited to hematoma and seroma, were seen in three patients, representing a complication rate of 11.8% in the examined population. Conclusions: Metacarpal non-union can be treated successfully via vascularized and non-vascularized bone grafting. Based on the available evidence, bone grafts demonstrate favorable union rates, post-operative pain reduction, hand function recovery, earlier bone fusion times, and minimal complications in the context of metacarpal non-union management.

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Section: Introductionmentioning

confidence: 99%