The development of a preliminary ultrasonographic scoring system for features of hand osteoarthritis

Keen, Helen; Lavie, Frédéric; Wakefield, Richard J.; D'Agostino, Maria Antonietta; Hammer, Hilde Berner; Hensor, Elizabeth M A; Pendleton, Adrian; Kane, David; Guérini, H.; Schueller-Weidekamm, Claudia; Kortekaas, M.C.; Birrel, F.; Kloppenburg, Margreet; Stamm, Tanja; Watt, Iain; Smolen, Josef S; Maheu, E.; Dougados, Maxime; Conaghan, Philip G.

doi:10.1136/ard.2007.077081

Cited by 129 publications

(120 citation statements)

References 21 publications

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“…The presence of osteophytes characterize the hand osteoarthritis [29][30][31]. We found osteophytes in 7 joints but in the absence of other pathological findings, especially cartilage abnormalities, we could not interpret their presence as belonging to osteoarthritis.…”

Section: Discussionmentioning

confidence: 54%

Ultrasonography of the metacarpophalangeal joints in healthy subjects using an 18 MHz transducer.

Fodor

Felea²,

Popescu³

et al. 2015

Med Ultrason

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Aim: To evaluate the metacarpophalangeal (MCP) joints (MCP2 and 5) in healthy subjects by ultrasonography (US) using a high frequency transducer (18 MHz) and to verify the interobserver agreement. Material and methods: We enrolled 50 healthy volunteers (37 women, age between 30-58 years, mean age 41.7 years, divided into 3 groups according to age: 30-39, 40-49, and 50-58 years). The subjects were successively evaluated by 4 rheumatologists: 2 experienced (team A) and 2 beginners (team B) in US. Seven dorsal and palmar longitudinal scanning positions and a supplementary scan for MCP cartilage were performed. The bone surface (erosions, osteophytes), the intra-articular content (synovial thickening and vascularization, 4 grade scale), and the aspect of the metacarpal head cartilage were analyzed. The anterior palmar recess was measured. The time for examination was recorded. Results: Erosions were detected in 7% of joints by team A and 2% by team B (p<0.05, kappa agreement 0.567) in subjects over 40 years. The agreement by team A in the detection of the erosions was very good (kappa value 0.83). A moderate positive correlation was obtained between the presence of erosions and age (r= 0.401, p=0.004). Osteophytes were identified only on the dorsal scan in subjects over 50 years (in 3.5% of joints team A, 1.5% team B, p>0.05, kappa value 0.421). No grade 1 synovitis was observed by team A but 4 joints with grade 1 synovitis were identified by team B (p<0.05) from the dorsal scan. The dimensions of the palmar recess had large distribution (MCP 2 between 0.55-1.3 mm; MCP 5 between 0.6-1.2 mm). No statistical significant differences were obtained when comparing the dimensions of the two hands or the values obtained in agegroups (all p>0.05). No statistical significant correlations were obtained between the dimensions of palmar recess and the body mass index or dominant hand (all p>0.05). No pathological findings were found in the examination of the metacarpal head cartilage. Power Doppler investigation found the presence of grade 1 signal in 2.5% joints by team A and 1.5% by team B (p>0.05) only in the dorsal scans. The mean time for examination was 7.8±1.74 min in team A and 13.78±2.96 min in team B (p<0.05). Conclusions: In healthy subjects pathological findings are occasionally encountered, especially erosions and osteophytes. Using an 18 MHz transducer the aspect of grade 1 synovitis was not encountered in healthy non-inflammatory MCP joints. There is a permanent need for standardized training and examination in musculoskeletal US.

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Section: Discussionmentioning

confidence: 54%

Ultrasonography of the metacarpophalangeal joints in healthy subjects using an 18 MHz transducer.

Fodor

Felea²,

Popescu³

et al. 2015

Med Ultrason

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“…As with MRI, most studies have assessed knee OA, although hip OA and more recently, the role of ultrasound in hand OA have also been examined [Keen et al 2008a].…”

Section: Ultrasoundmentioning

confidence: 99%

The role of synovitis in osteoarthritis

Wenham

Conaghan

2010

Therapeutic Advances in Musculoskeletal

139

109

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Osteoarthritis (OA) is the most common form of arthritis worldwide yet there is still a lack of effective treatments for this condition. Increasingly, attention has turned to the role of the synovium in OA as it is now recognized, in part from the use of modern imaging techniques, that synovitis is both common and associated with pain. This offers a target for treatment, for both symptom and potential structure modification. In this review we discuss the evidence for histological and imaging-detected synovitis and the current role of antisynovial therapies in OA.

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“…Recently, development of a preliminary US scoring system for hand OA provided interesting basis for the development of an US outcome tool that has the potential to be used in clinical trials [63].…”

Section: Research Agendamentioning

confidence: 99%

Imaging the joint in osteoarthritis: a place for ultrasound?

Iagnocco

2010

Best Practice & Research Clinical Rheumatology

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Ultrasound (US) is a valuable tool for imaging musculoskeletal changes in osteoarthritis. It shows early and late findings related to inflammation and structural damage. Sonography is a safe tool, which has recently registered an increasing and widespread use, it being considered as a bedside procedure in the clinical assessment of rheumatic patients. Its applications in osteoarthritis are related to easy accessibility of equipment, low cost, short duration of single examinations and the possibility of performing a multiregional joint evaluation in the same scanning session. Permitting an extensive evaluation of most joint changes present in osteoarthritis, it gives the opportunity to monitor disease progression and perform a follow-up of the response to different local and systemic treatments. US-guided procedures are commonly performed with safety, reliability and optimal patient tolerance. Development in technology and technique with improvement of new research studies will further amplify the diagnostic role of ultrasound in osteoarthritis in the near future. (C) 2009 Elsevier Ltd. All rights reserved

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The development of a preliminary ultrasonographic scoring system for features of hand osteoarthritis

Cited by 129 publications

References 21 publications

Ultrasonography of the metacarpophalangeal joints in healthy subjects using an 18 MHz transducer.

Ultrasonography of the metacarpophalangeal joints in healthy subjects using an 18 MHz transducer.

The role of synovitis in osteoarthritis

Imaging the joint in osteoarthritis: a place for ultrasound?

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