Wilhelm Conrad Roentgen, renowned as the father of radiology, was born in 1845 in Germany. In 1895, he discovered X-rays, a form of radiation capable of passing through objects and producing images on screens and plates. This discovery revolutionized medicine and marked the beginning of a new era. X-rays found their greatest triumph in medicine, enabling the visualization of internal structures of the body without the need for invasive procedures. From bone X-rays to anatomy and pathology studies, X-rays became an invaluable tool for doctors. Later, advanced techniques were developed, which further expanded the scope of X-rays in the diagnosis and treatment of various diseases. Roentgen was noted for his modesty and generosity in freely sharing his findings with the scientific community. Radiology has evolved with the use of techniques such as computed tomography and PET-CT (Positron Emission Tomography-computed Tomography), which provide three-dimensional images with surprising precision. In addition, artificial intelligence and machine learning tools are being used to improve diagnostic accuracy. On the centenary of his passing, we remember Roentgen as a pioneer whose legacy lives on in modern medicine. His work lives on, inspiring successive generations in scientific inquiry.