The development of the Metabolic-associated Fatty Liver Disease during pharmacotherapy of mental disorders - a review

Rogalski, Jakub; Subdys, Aleksandra; Gawlik-Kotelnicka, Oliwia

doi:10.2478/cpp-2022-0013

Cited by 4 publications

(3 citation statements)

References 100 publications

(211 reference statements)

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“…Numerous somatic comorbidities in the course of BD, including cardiovascular and metabolic ones, are often observed, which in turn contribute to significant premature mortality [40,41]. Addictions to psychoactive substances and alcohol, poor physical activity or psychosocial functioning and metabolic side effects of applied psychopharmacotherapy may contribute to this state [42][43][44][45]. Wulsin et al made a point that individuals with type I BD have a significantly lower omega-3 index in comparison to the healthy controls [46].…”

Section: Role Of N-3 Pufas In the Acute Phase Of The Bipolar Disorder...mentioning

confidence: 99%

The role of Omega-3 Polyunsaturated Fatty Acids in the treatment of Bipolar Disorder – a narrative review

Rogalski,

Pokrywka,

Tomczak

2024

Med Srod.

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Introduction and Objective. Bipolar Disorder (BD) is a chronic mental condition associated with significant impairment of psychosocial functioning and premature mortality due to somatic comorbidities, as well as high rates of completed suicides. Unfortunately, results of currently available methods of treatment are unsatisfactory. Thus, new therapeutic solutions are sought. Recently, particular attention has been paid to the use of nutraceuticals, especially Omega-3 Polyunsaturated Fatty Acids (n-3 PUFAs), as an adjunctive treatment in various mental disorders. The aim of the review is to show the role of PUFAs in the pathogenesis of BD, and present results of already conducted studies investigating n-3 PUFAs supplementation effects on the BD clinical course. Materials and Method. Internet scientific bases were searched throughout January and February 2024 for the relevant to this topic literature from the past 15 years, using keywords: "bipolar disorder", "cardiovascular risk", "mental disorders", "omega-3 fatty acids", "polyunsaturated fatty acids", "remission", "treatment". Original and review articles were included. Manuscripts in other language than English were excluded from the search. To assess the proper quality of this manuscript, the Scale for the Assessment of Narrative Review Articles were used. Brief description of the state of knowledge. There is lack of research assessing the importance of n-3 PUFAs in the treatment of BD. However, it seems that their supplementation may bring significant benefits in the acute phase of depression episode treatment, remission maintenance and reduction in cardiometabolic risk factors. Summary. Results of already conducted studies should be treated as a rationale for future research. It is highly recommended to confirm the n-3 PUFAs efficiency in the BD treatment, to justify their widespread use in everyday clinical practice.

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Section: Role Of N-3 Pufas In the Acute Phase Of The Bipolar Disorder...mentioning

confidence: 99%

The role of Omega-3 Polyunsaturated Fatty Acids in the treatment of Bipolar Disorder – a narrative review

Rogalski,

Pokrywka,

Tomczak

2024

Med Srod.

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“…Particular caution should be paid when using first-generation antipsychotic drugs due to the risk of extrapyramidal symptoms and hyperprolactinemia [41]. Furthermore, in the case of SGAs, metabolic repercussions in terms of carbohydrate and lipid metabolism should be also taken into account [42]. Therefore, these side effects may limit their augmentation.…”

Section: Antipsychoticsmentioning

confidence: 99%

Pharmacological Support Treatment of Non-Suicidal Self-Injuries Among Children and Adolescents: A Narrative Review

Rogalski,

Tomczak

2024

hpc

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Non-suicidal self-injuries (NSSI) constitute a significant problem among children and adolescents, especially during the global burden of mental disorders worldwide. Moreover, such behaviors are perceived as a risk factor for the suicidal behaviors occurrence in the future. Thus, it would appear necessary to search for effective forms of their treatment. A pharmacological approach may play a supportive role. This study is a narrative review summarizing scientific reports on possible pharmacological support treatment of NSSI among children and adolescents. Internet scientific bases were searched for literature, including original research, review articles and case reports. There are many possible pharmacological interventions that may reduce the incidence of self-harm behaviors. Antihistamines and neuroleptics can be used successfully in the acute phase. In turn, second-generation antipsychotics and potentially naltrexone seem to be the most effective in long-term treatment. Although psychotherapy is the basic form of NSSI treatment, a psychopharmacological approach may play an essential role in Health Problems of Civilization

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“…However, it is worth noting that their use is off-label in most of cases among children and adolescents. It may be also associated with numerous side effects [34,35].…”

Section: Biological Factors 1chronic Painmentioning

confidence: 99%

Risk factors of the depressive and anxiety disorders development among patients with Adolescent Idiopathic Scoliosis and possible therapeutic interventions

Tomczak,

Rogalski

2024

Curr Probl Psychiatry

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Introduction: Adolescent idiopathic scoliosis is a common type of scoliosis among adolescents. A significant problem is the coexistence of depressive and anxiety disorders. However, the causes of this condition are not fully recognized. Thus, it seems reasonable to search for possible risk factors that may trigger mental disorder occurrence. Material and methods: This is a literature narrative review concentrating on the influence of the adolescent idiopathic scoliosis on the development of depression and anxiety disorders among adolescents, as well as possible therapeutic interventions. Google Scholar, Medline, PubMed and Science Direct databases were searched throughout January 2024 for relevant original and review articles from 2000 to 2024, using the following keywords: “adolescent idiopathic scoliosis”, “anxiety”, “body image”, “bracing”, “chronic disease”, “depression”, “mental disorders”, “pain”, “peer relationship”, “physical activity”, “pulmonary function”, “sleep disorders”, “surgery”, “treatment”. Manuscripts in other language than Polish or English were excluded from the search. To ensure the appropriate quality of this review, the Scale for the Assessment of Narrative Review Articles was used. Results: Chronic pain, sleep disorders, pulmonary function impairment, perception of the disease as a chronic somatic disease, disturbed body image, lack of social interactions, physical activity limitation and applied methods of treatment may lead to the depressive and anxiety disorders development in the adolescent idiopathic scoliosis course. Conclusions: Biological and psychosocial factors contribute to the pathogenesis of depressive and anxiety disorders among patients with adolescent idiopathic scoliosis. Their identification should help create a comprehensive plan of treatment, which may effectively maximize therapeutic outcomes in the context of both scoliosis and mental disorders. Keywords: depression, risk factors, anxiety, adolescent idiopathic scoliosis, mental health

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The development of the Metabolic-associated Fatty Liver Disease during pharmacotherapy of mental disorders - a review

Cited by 4 publications

References 100 publications

The role of Omega-3 Polyunsaturated Fatty Acids in the treatment of Bipolar Disorder – a narrative review

The role of Omega-3 Polyunsaturated Fatty Acids in the treatment of Bipolar Disorder – a narrative review

Pharmacological Support Treatment of Non-Suicidal Self-Injuries Among Children and Adolescents: A Narrative Review

Risk factors of the depressive and anxiety disorders development among patients with Adolescent Idiopathic Scoliosis and possible therapeutic interventions

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