The development of the suprarenal gland in the albino rat, with a consideration of its possible relation to the origin of foetal movements

Pankratz, David S.

doi:10.1002/ar.1090490105

Cited by 48 publications

(8 citation statements)

References 15 publications

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“…On the other hand, there is a remarkable consistency throughout the species reviewed with regard to the size of the developing fetuses at this stage. This includes studies of the rabbit (Mitsukuri, 1882;Kohn, 1903), cat (Davies, 1937), guinea pig (Harmon and Derbyshire, 1932), insectivores (Adams, 1958), rat (Pankratz, 1931;Elfvin, 1967;Daikoku et al, 1969), mouse (Miller, 1926;Waring, 1936;Fernholm, 1971;Theiler and Muntener, 1974), pig (Stadnicka and Van Wynsberghe, 19821, and man (Keene et al, 1927;Crowder, 1957;Coupland, 1952Coupland, , 1965Hervonen, 1971). Our data from the opossum agree with these studies; thus, it may be important to note that this critical phase in the development of the mammalian adrenal medulla is initiated in fetuses of a characteristic size (14-20 mm crown-rump length).…”

Section: Discussionmentioning

confidence: 99%

Opossum adrenal medulla: I. Postnatal development and normal anatomy

et al. 1987

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The anatomy and histology of the adrenal gland in the adult opossum were found to be typical for mammals. The development of the adrenal medulla was also found to follow the typical mammalian pattern. Primitive sympathetic cells were found in both intra- and extra-adrenal locations in the newborn at a time when chromaffin precursor cells were migrating to the adrenal anlage. Pheochromoblasts first appeared within the forming medulla where at a later stage chromaffin cells could be observed forming columns of cells between adjacent sinusoids. Unlike in other mammals, much of this development takes place postnatally when the neonate is in the mother's marsupium. The value of the developing opossum adrenal medulla as an experimental model is stressed, since a significant amount of development takes place in an environment that is accessible to experimental manipulation.

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Section: Discussionmentioning

confidence: 99%

Opossum adrenal medulla: I. Postnatal development and normal anatomy

et al. 1987

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“…These studies speculated that the adrenal cortex originates from the dorsal coelomic epithelia lying between the dorsal mesentery and the developing urogenital ridge (Pankratz 1931;Uotila 1940), the underlying mesenchymal cells (Roos 1966), or both the epithelial and the mesenchymal cells (Gruenwald 1942a). The cell populations in similar regions were also presumed to be the blastemas for the gonads (Whitehead 1904;Fischel 1930;Gruenwald 1942a,b;Torry 1945;Zamboni & Upandhyay 1982;Satoh 1985;Byskov 1986).…”

Section: From the Adreno-genital Primordium To Mature Steroidogenic Tmentioning

confidence: 99%

The ontogenesis of the steroidogenic tissues

Morohashi

1997

Genes to Cells

105

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Based on the common function of steroid hormone-producing tissues and homologous regulation by the hypothalamo-pituitary axis, the adrenal cortex and the gonads have been suggested to have an intimate ontogenic relationship. This assumption is also supported by the findings of common transcription factors implicated in the differentiation of both types of tissue and further supported by concomitant defects in such tissues due to the disruption of a single gene. Similarly, simultaneous anomalies in those tissues are also observed in some diseases caused by mutations of the genes encoding those transcription factors. A recent immunohistochemical study with one of the transcription factors, Ad4BP/SF-1, definitely demonstrated the presence of a particular cell population designated the 'adreno-genital primordium (AGP)' which gives rise to both the adrenal cortex and the gonads. In the process of differentiation from the AGP to the mature adrenal cortex and the gonads of the two sexes, several interesting issues can be raised as to the next targets for the study. To address these issues it is important to elucidate the upstream regulatory mechanisms and downstream target genes of such transcription factors as WT1, SRY, SOX9 and DAX1, in addition to Ad4BP/SF-1, all of which are implicated in steroidogenic tissue differentiation.

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“…In the developing rat, primitive sympathetic cells coalesce to form the sympathetic chains at approximately embryonic day 12 (E12) and invade the primordium of the adrenal cortex during the next 48 h (Pankratz, 1931). Identifiable progenitor cells disappear in the postnatal period.…”

Section: Embryonic Developmentmentioning

confidence: 99%