The diagnosis and management of suspected lymphoma in general practice

Abstract

With rapid advancements in diagnosis and treatment of malignancies, the gap between generalists and subspecialists continues to widen, particularly in cancers like lymphoma where the spectrum of disease varies from indolent to rapidly progressive.Prior to establishing with a hematologist/oncologist, patients must be accurately and comprehensively diagnosed and managed for lymphoma in the generalist setting. In the following manuscript, we review the common clinical presentations in which should raise concern for lymphoma. We summarize the literature regarding the role of laboratory studies including complete blood count and peripheral blood flow cytometry, the recommendations for lymph node sampling, the role and selection of imaging modalities, and ideal patient monitoring for high-risk clinical syndromes that may be encountered in lymphoma.

Whole‐Cell Electrochemical Aptasensors for Cancer Diagnosis: Current Advances and Prospects

“…Lymphoma is a diverse group of lymphoid neoplasms with marked differences in clinical course and response to treatment. [ 67 ] Lymphomas are classified according to their postulated normal cell type of origin (B‐cell vs T‐cell), morphology (Hodgkin vs non‐Hodgkin), and level of cellular differentiation. [ 68 ] In 2010, Ding and co‐workers demonstrated TD05 aptamers by using electrochemical and ECL techniques to investigate the best LOD from different modified treatments of the aptamers against Ramos cells (a human B‐cell lymphoma).…”