The diagnosis and management of chronic cough

Morice, Alyn H.

doi:10.1183/09031936.04.00027804

Cited by 468 publications

(437 citation statements)

References 121 publications

(126 reference statements)

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“…When a diagnosis was suggested, the most common cause was asthma (23%). Gastro-oesophageal reflux disease and upper airway cough syndrome (post-nasal drip) were also common causes, consistent with previous studies of cough that investigated subjects with the Anatomic Diagnostic Protocol as recommended by chronic cough guidelines [12, [16][17][18]. As expected, some respondents reported multiple causes of cough.…”

Section: Discussionsupporting

confidence: 88%

“…The reasons why other prescribed and overthe counter medications were ineffective are unclear, and was beyond the scope of this study. Inadequate assessment of patients, dose/duration and non-compliance of medications and misdiagnosis could all be potential explanations [16,17]. The reasons for treatment failure warrant further investigation.…”

Section: Discussionmentioning

confidence: 99%

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The Impact of Chronic Cough: A Cross-Sectional European Survey

Chamberlain

Garrod

Douiri

et al. 2015

Lung

215

193

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

The Impact of Chronic Cough: A Cross-Sectional European Survey

Chamberlain

Garrod

Douiri

et al. 2015

Lung

215

193

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“…Multiple prospective studies [11,12] have previously asserted that the majority of cases of chronic cough in adults are associated with one or more of three aetiological groups: rhinosinusitis or upper airway cough syndrome; eosinophilic airway inflammation; and gastro-oesophageal reflux. This view is enshrined in guidelines [13,14]. However, only a small minority of individuals with these common conditions actually complain of a chronic cough.…”

Section: Resultsmentioning

confidence: 99%

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

et al. 2014

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In 2011, a European Respiratory Society Task Force embarked on a process to determine the position and clinical relevance of the cough hypersensitivity syndrome, a disorder characterised by troublesome coughing often triggered by low levels of thermal, mechanical or chemical exposure, in the management of patients with chronic cough. A 21-component questionnaire was developed by an iterative process supported by a literature review. 44 key opinion leaders in respiratory medicine were selected and interviewed as to their opinions.There was a high degree of unanimity in the responses obtained, with all opinion leaders supporting the concept of cough hypersensitivity as a clinically useful paradigm. The classic stratification of cough into asthmatic, rhinitic and reflux-related phenotypes was supported. Significant disparity of opinion was seen in the response to two questions concerning the therapy of chronic cough. First, the role of acid suppression in reflux cough was questioned. Secondly, the opinion leaders were split as to whether a trial of oral steroids was indicated to establish a diagnosis of eosinophilic cough.The cough hypersensitivity syndrome was clearly endorsed by the opinion leaders as a valid and useful concept. They considered that support of patients with chronic cough was inadequate and the Task Force recommends that further work is urgently required in this neglected area. @ERSpublications Cough hypersensitivity syndrome was clearly endorsed by opinion leaders as a valid and useful concept

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“…The frequently unsuccessful effort to treat refractory cough represents a huge source of frustration for patient and physician alike. Indeed, the significance of chronic cough as a clinical issue is clearly demonstrated by the fact that, in the past decade, no fewer than six major respiratory societies worldwide have published guidelines on the diagnosis and management of chronic cough [2][3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Thoughts on One Thousand Chronic Cough Patients

Dicpinigaitis

2012

Lung

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Cough is the most common complaint for which patients seek medical attention. Although most cases of acute cough, due to viral upper respiratory tract infection, are transient and self-limited, chronic cough often poses a diagnostic and therapeutic challenge. A subgroup of patients suffering from chronic cough will elude a diagnosis despite appropriate evaluation, and will prove refractory to all therapeutic intervention. Having personally evaluated 1000 individuals presenting to a specialty cough center, the author shares insights regarding the demographic composition of this unique group of patients, as well as clinical observations and opinions on currently unmet needs requiring further research.

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The diagnosis and management of chronic cough

Cited by 468 publications

References 121 publications

The Impact of Chronic Cough: A Cross-Sectional European Survey

The Impact of Chronic Cough: A Cross-Sectional European Survey

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

Thoughts on One Thousand Chronic Cough Patients

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