The diagnosis and management of sinusitis: A practice parameter update

Slavin, Raymond G.; Spector, Sheldon L.; Bernstein, I. Leonard; Kaliner, Michael; Kennedy, David W.; Virant, Frank S.; Wald, Ellen R.; Khan, David A.; Blessing-Moore, Joann; Lang, David M.; Nicklas, Richard A.; Oppenheimer, John; Portnoy, Jay M.; Schuller, Diane E.; Tilles, Stephen A.; Borish, Larry; Nathan, Robert A.; Smart, Brian A.; Vandewalker, Mark

doi:10.1016/j.jaci.2005.09.048

Cited by 332 publications

(394 citation statements)

References 238 publications

(211 reference statements)

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“…1,2,8,9 NPs frequently complicate this condition, and, as such, their presence (especially in the concomitant presence of asthma) has been proposed as presumptive diagnostic evidence for an underlying eosinophilic disease. 10,11 However, CHES can only be unambiguously diagnosed on histochemical staining of tissue for eosinophils or via quantification of eosinophil-derived mediators (such as eosinophil cationic protein or major basic protein). 12 In CHES, the sinus tissue shows a marked increase in cells that express cytokines (IL-5, granulocyte macrophage colony-stimulating factor, etc.…”

Section: Immune Mechanisms Of Chesmentioning

confidence: 99%

Chronic sinusitis pathophysiology: The role of allergy

Kennedy

Borish

2013

Am J Rhinol�Allergy

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Section: Immune Mechanisms Of Chesmentioning

confidence: 99%

Chronic sinusitis pathophysiology: The role of allergy

Kennedy

Borish

2013

Am J Rhinol�Allergy

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“…Currently, RS is one of the dis-eases that most commonly affects the respiratory tract (Roberts, 2007;Slavin et al, 2005), and the action of viruses, bacteria and fungi play an important role in its etiology, with exposures to poor air quality in the environment, ciliary impairment, and allergy being the most common factors associated with RS (Dykewicz and Hamilos, 2010;Fokkens et al, 2012;Magrysı´ et al, 2011). Nevertheless, its true prevalence is unclear, since not all individuals seek care, and because there is a deficit of epidemiological studies exploring its prevalence (File, 2006;Fokkens et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Differentiating between rhinosinusitis and mastoiditis surgery from postmortem medical training: A study of two identified skulls and hospital records from early 20th century Coimbra, Portugal

Magalhães

Lopes

Santos

2017

International Journal of Paleopathology

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Differentiating between medical procedures performed antemortem, perimortem or postmortem in skeletal remains can be a major challenge. This work aims to present evidence of procedures to treat rhinosinusitis (RS) and mastoiditis, suggest criteria for the diagnosis of frontal sinus disease, and frame the individuals described in their medical historical context. In the International Exchange collection, the skull (878) of a 24-year-old male, who died in 1933 due to frontal sinusitis and meningitis, presents evidence of a trepanation above the right frontonasal suture, and micro/macroporosity on the superciliary arches. The available Coimbra University Hospitals archives reported that 46 females and 59 males (aged 15 months-84 y.o., x− = 35.33) underwent surgery to treat RS, primarily by trepanation (94.3%). In a search for similar evidence in the collection, the skull of a 42-year-old female (85), who died in 1927 due to sarcoma in the abdomen, shows four quadrangular holes located above the right supraorbital notch, right and left maxilla, and left mastoid process. The number/location of the holes and cut marks point to postmortem medical training (possible dissection). This paper discusses the value of information from historical contexts to differentiate between surgery and medical training in the paleopathological record.

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“…Guidelines for the diagnosis and treatment of rhinosinusitis differ in terms of diagnosis of CRS and therapy; oral and intranasal corticosteroids are the standard therapy for CRS and NP [6][7][8][9][10]. Glycosaminoglycans (GAGs) also known as mucopolysaccharides, are long unbranched chains of disaccharide units that are repeated in the determined order by alternating an amminosaccaride (containing an amino group instead of a simple-OH group) to a monosaccharide usually acid (containing one or more carboxyl groups and/or sulphates and thus negative charges).…”

Section: Introductionmentioning

confidence: 99%

Hyaluronan in the Treatment of Chronic Rhinosinusitis with Nasal Polyposis

Cassandro

Chiarella

Cavaliere

et al. 2014

Indian J Otolaryngol Head Neck Surg

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Chronic rhinosinusitis (CRS) is a common condition and affects the quality of life of approximately 16 % of adults in US and 10.9 % in Europe. Hyaluronan (HA) is a nonsulphate glycosaminoglycan found in the extracellular matrix of connective tissues, and plays an important role in the healing process and repair of mucosal surfaces. We aim to evaluate the effect of HA on nasal symptoms and endoscopic appearance in patients with CRS and nasal polyps (NP) who have not undergone sinus surgery. Eighty patients older than 18 years old were randomized to receive either open-label nebulized saline solution (NS) or intranasal corticosteroid spray (ICS) 200 lg bid or nebulized sodium hyaluronate (NHA, YABRO Ò ) or both ICS and NHA. Results were collected at 1 month, 3 months and 3 months after treatment. Significant improvements in nasal symptoms scores, endoscopic appearance scores, radiologic scores, rhinomanometry and saccharine clearance test were observed in the NHA, ICS and ICS ? NHA groups after 1 month and 3 months of treatment compared with baseline (all p B 0.005). The use of oral steroids was significantly reduced after 3 months of therapy in the same groups versus baseline (all p \ 0.05). The incidence of adverse events at 3 months was similar between the 4 groups (all p [ 0.05). Throat irritation, nasal burning and drug-related epistaxis were not reported in the group NHA. HA, as a nebulized nasal douche preparation, improved nasal symptoms and endoscopic appearances in patients with CRS and NP who have not undergone sinus surgery.

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The diagnosis and management of sinusitis: A practice parameter update

Cited by 332 publications

References 238 publications

Chronic sinusitis pathophysiology: The role of allergy

Chronic sinusitis pathophysiology: The role of allergy

Differentiating between rhinosinusitis and mastoiditis surgery from postmortem medical training: A study of two identified skulls and hospital records from early 20th century Coimbra, Portugal

Hyaluronan in the Treatment of Chronic Rhinosinusitis with Nasal Polyposis

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