The Diagnosis and Treatment of Acute Cough in Adults

Holzinger, Felix; Beck, Stefanie; Dini, Lorena; Stöter, Christiane; Heintze, Christoph

doi:10.3238/arztebl.2014.0356

Cited by 30 publications

(32 citation statements)

References 41 publications

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“…Among nine evidence-based guidelines, four used the Grading of Recommendations Assessment, Development and Evaluation system [21][22][23][24] ; four used the American College of Chest Physicians (CHEST), 2,25,26 Scottish Intercollegiate Guidelines Network, 27 Société Scientifique de Medicine Générale, 28 and National Health and Medical Research Council 29 grading systems; and one (Clinical Expert Guidelines for the Management of Cough in Lung Cancer) 30 did not mention which grading system was adopted. Despite the use of five grading systems, these schemes were based on the same criteria and comparable structures.…”

Section: Strength Of Recommendation and Level Of Evidencementioning

confidence: 99%

“…Therefore, a composite grading system was generated to represent all recommendations ( Table 1). Only three guidelines 2,22,23 included the updated version, but the first version of the two German cough guidelines 22,23 were not published in English. Because the latest version of the CHEST guideline (in 2014) has not been completely updated, we compared the level of evidence and strength of recommendations between the second version and the latest version for the available contents.…”

Section: Strength Of Recommendation and Level Of Evidencementioning

confidence: 99%

“…Of the 15 CPGs, five were developed by international organizations 2,32,33 or were from > 1 country. 27,29 The remaining guidelines were from Australia, 21 Belgium, 28 China, 34 Germany, 22,23 the United Kingdom, 30,35,36 Japan, 37 and Korea. 24 Four guidelines (26.7%) targeted both adults and children.…”

Section: General Characteristicsmentioning

confidence: 99%

See 2 more Smart Citations

A Critical Review of the Quality of Cough Clinical Practice Guidelines

Jiang

Guan

Zheng

et al. 2016

Chest

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Section: Strength Of Recommendation and Level Of Evidencementioning

confidence: 99%

Section: Strength Of Recommendation and Level Of Evidencementioning

confidence: 99%

See 1 more Smart Citation

A Critical Review of the Quality of Cough Clinical Practice Guidelines

Jiang

Guan

Zheng

et al. 2016

Chest

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“…Herbal medicinal products containing plant-derived monoterpenes provide a well-tolerated alternative for the symptomatic treatment of inflammatory airway diseases [17][18][19]. Several clinical studies showed improved symptom relief in adults suffering from acute bronchitis with plant preparations containing 1,8-cineole and/or linalool when compared to placebo [20][21][22][23][24][25][26].…”

Section: Original Articlementioning

confidence: 99%

Spicae aetheroleum in uncomplicated acute bronchitis: a double-blind, randomised clinical trial

Kähler

Dereziński²,

Bocian-Sobkowska³

et al. 2017

Wien Med Wochenschr

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SummaryBackground The trial aimed to evaluate the efficacy and safety of Spicae aetheroleum (Spicae ae.), a phytomedicine obtained by steam distillation of the flowering tops of Lavandula latifolia, as compared to placebo in adult patients with acute bronchitis. Methods Patients with uncomplicated acute bronchitis (bronchitis severity score [BSS] ≥ 5 score points) were randomly assigned to treatment with Spicae ae. or placebo in a double-blind, parallel-group design. No additional treatment was admitted. The primary objective was the mean difference of a defined total BSS of 25% between the Spicae ae. and the placebo group after 7 days of full medication dose. Secondary endpoints included the BSS at day 10, additional signs and symptoms of bronchitis, quality of life (QoL) and safety. Results The mean decrease in BSS at day 7 and day 10 was significant with 4.79 vs. 3.20 (p < 0.005 for a 25% difference) and 6.47 vs. 4.32 (p < 0.009 for a 25% difference) score points respectively in the Spicae ae. (n = 119) vs. placebo group (n = 110). Accordingly, most additional signs and symptoms of acute bronchitis as well as the patients' QoL improved significantly with Spicae ae. as compared to placebo. In all, 258 patients were eligible for safety analysis. The treatment with Spicae ae. was well tolerated; no serious adverse events occurred. Conclusion The defined objectives both for the primary and secondary endpoints have been met. The results of this study provide evidence that Spicae ae. is well tolerated, effective and superior to placebo in the symptomatic treatment of uncomplicated acute bronchitis in adult patients.

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“…Dies begünstigt die Resistenzentwicklung gegen die angewandten Antibiotika und ihr unnötiger Einsatz verursacht unerwünschte Nebenwirkungen wie z. B. Durchfälle sowie zusätzliche Kosten [6][7][8].…”

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Antibiotikaeintrag in das urbane Abwasser

Timpel

Marx

Knoth

et al. 2015

Bundesgesundheitsbl.

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Antibiotics are essential for the successful treatment of bacterial infections. Recently, the increasing number of resistant bacteria and the occurrence of residues of antibiotics in the environment has become the focus of scientific interest. The aim of the cooperative project ANTI-Resist was to investigate the release of antibiotics and the occurrence and distribution of antibiotic resistance in the urban waste water system of the city of Dresden.This article presents the main results of the secondary data analysis for the determination of outpatient and inpatient antibiotic consumption and provides an insight into the complexity of the topic antibiotics in waste water.Based on the data of outpatient prescriptions provided by the AOK PLUS for the period 2005 to 2013, thirteen focus substances were identified to estimate antibiotic consumption. Furthermore, delivery data from the pharmacies of three hospitals in Dresden were available.Depending on the substances investigated, seasonality and age dependency were determined. The results at a regional level were mostly in good accordance with general trends throughout Germany. It should be noted that the total amount of antibiotics used remained nearly constant over the whole period investigated, but the prescription of fluoroquinolones increased. This must be questioned when taking into account the increasingly critical situation in the treatment of Gram-negative bacteria in particular. Examinations of waste water conducted indicated that sewage treatment plants are not able to remove antibiotics or their metabolites completely from waste water. The residues are released into surface waters via the treatment plants. The impact cannot be assessed at the moment and further investigations are necessary.

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The Diagnosis and Treatment of Acute Cough in Adults

Cited by 30 publications

References 41 publications

A Critical Review of the Quality of Cough Clinical Practice Guidelines

A Critical Review of the Quality of Cough Clinical Practice Guidelines

Spicae aetheroleum in uncomplicated acute bronchitis: a double-blind, randomised clinical trial

Antibiotikaeintrag in das urbane Abwasser

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