The Diagnosis of Food Allergy

Rinkel, Herbert J.; Lee, Carleton H.; Brown, Dor W.; Willoughby, James W.; Williams, John

doi:10.1001/archotol.79.1.87

Cited by 6 publications

(6 citation statements)

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“…The end-point dilution method of skin testing, however, was developed by Lee in 1959 and described in 1964 in conjunction with Rinkel et al 20 The value of the technique is still not proved, but its adherents describe it as an effective diagnostic procedure.…”

Section: Dietary Exclusion Methodsmentioning

confidence: 99%

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Does food intolerance have any role in the aetiology and management of rheumatoid disease?

Darlington¹

1985

Annals of the Rheumatic Diseases

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Section: Dietary Exclusion Methodsmentioning

confidence: 99%

“…This conference will be held in Monte Carlo on [19][20][21][22] March 1986 and will discuss the progress made in the field of antirheumatic drugs, analgesics, antipyretics, and immunomodulators. Details from the Organizing Secretariat, ALM s.r.l., Via Lattuada, 26-20135 Milan, Italy.…”

Section: Conference On Drug Toxicity and Compliancementioning

confidence: 99%

Does food intolerance have any role in the aetiology and management of rheumatoid disease?

Darlington¹

1985

Annals of the Rheumatic Diseases

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“…It is noteworthy, however, that KA who was shown to be intolerant of peas, reportedly had a positive skin test to peas in the past but we were unable to confirm this. 19 Only the first two have proven their worth in the field although the sheer profusion of tests is a testimony to the reality that they too have shortcomings.20 21 We have found RAST and skin tests unhelpful in the diagnosis of specific food intolerance in our patients. We have, however, shown the diagnostic role of placebo controlled, double blind food challenge.…”

Section: Rast and Skin Testsmentioning

confidence: 88%

Specific food intolerance: its place as a cause of gastrointestinal symptoms.

Farah¹,

Calder²,

Benson³

et al. 1985

Gut

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Irritable bowel syndrome, for instance, was recently reported to be largely a manifestation of food intolerance.7 Despite this, and the extravagant claims recently made for food allergy notwithstanding, it is likely that food allergy is an underdiagnosed condition.8 This may, however, be obscured by the exaggerated impression of prevalence gained from studies involving highly selected population samples. Without previous regard to the mechanism involved, we therefore proposed to seek specific food intolerance among patients with unexplained gastrointestinal symptoms.One of the reasons for the scepticism surrounding the subject of food intolerance is the absence of simple and reliable tests for diagnosis. Double blind food challenges are required to establish diagnosis and a number of techniques using this approach are available. In view of the recognition that food induced symptoms may be delayed9 10 and to ensure, therefore, that chronic food intolerance sufferers with late onset of symptoms were not missed, we used food challenges over one week periods, repeated as necessary if more than one food was suspected. The challenges were double blind and placebo controlled.

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“…sometimes referred to respectively as fixed and cyclic. [1][2][3][4] The immediate-fixed variety represents only 5% of food hypersensitivity, and presents as a consistent Gell and Coombs" Type I IgE-mediated reaction. The usual cause-and-effect history of rather spectacular symptom production more often provides an obvious diagnosis, and confirmation may be accomplished by radioallergosorbent (RAST) or skin testing.…”

mentioning

confidence: 99%

Efficacy of Alternative Tests for Delayed‐Cyclic Food Hypersensitivity

King¹,

Rubin²,

Fadal³

et al. 1989

Otolaryngol.--head neck surg.

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With the oral challenge food test (OCFT) used as the standard for delayed-cyclic food hypersensitivity diagnosis, blinded comparison studies were accomplished with 175 in vitro food specific IgE and 180 IgG radioallergosorbent tests, 180 food enzyme-linked immune complex assays, and 155 in vivo Multi-Test prick tests. The study was multi-centered, eight physicians and 37 patients participating. All of the compared tests were shown to be approximately 50% efficient when compared with the OCFT results, and, thus, nonefficacious.

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The Diagnosis of Food Allergy

Cited by 6 publications

References 0 publications

Does food intolerance have any role in the aetiology and management of rheumatoid disease?

Does food intolerance have any role in the aetiology and management of rheumatoid disease?

Specific food intolerance: its place as a cause of gastrointestinal symptoms.

Efficacy of Alternative Tests for Delayed‐Cyclic Food Hypersensitivity

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