2021
DOI: 10.1111/pai.13667
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The Dietary Inflammatory Index and asthma burden in children: A latent class analysis

Abstract: Introduction Unbalanced dietary intake has been increasingly recognized as an important modifiable risk factor for asthma. In this study, we assessed whether a pro‐inflammatory diet is associated with higher asthma burden in three steps: (1) identification of asthma latent classes (LC) based on symptoms, indoor exposures, and pulmonary function; (2) identification of risk factors associated with LC membership; and (3) estimation of the probabilities of LC membership with variation in DII. Methods A cross‐secti… Show more

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Cited by 13 publications
(9 citation statements)
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“…It was even shown that an unsupervised elimination diet in childhood might lead to malnutrition, growth retardation, vitamin deficiencies and associated health issues (22,35). In the context of this study, a pro-inflammatory diet consumed by the children might worsen the atopic outcome itself (20) and furthermore reduce their buffering capacity against harmful environmental exposures or triggers. An optimal nutritional status was described to be protective against both communicable and non-communicable diseases (36).…”
Section: Discussionmentioning
confidence: 75%
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“…It was even shown that an unsupervised elimination diet in childhood might lead to malnutrition, growth retardation, vitamin deficiencies and associated health issues (22,35). In the context of this study, a pro-inflammatory diet consumed by the children might worsen the atopic outcome itself (20) and furthermore reduce their buffering capacity against harmful environmental exposures or triggers. An optimal nutritional status was described to be protective against both communicable and non-communicable diseases (36).…”
Section: Discussionmentioning
confidence: 75%
“…For example, in children, a pro-inflammatory diet was not associated with current asthma or lung function, but in children with allergic airway inflammation, a higher DII score was associated with a 2.38 fold higher risk of wheezing (43). In addition, a pro-inflammatory diet was associated with asthma (20). Further, it was shown that higher inflammatory potential of the maternal diet was associated with increased odds of offspring asthma and/or wheeze by age 4 years, although results attenuated into non-significance after adjustment for confounders (44).…”
Section: Discussionmentioning
confidence: 97%
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“…Asthma is the leading noncommunicable disease, causing a burden on the health of children [1]. The prevalence of childhood asthma in the USA has been reported to be 7.8% [2].…”
Section: Introductionmentioning
confidence: 99%
“…A western diet, characterized by high intake of saturated fats, sugar, and ultraprocessed foods and low intake of fiber, has been associated with the increased risk of allergic and chronic inflammatory conditions [ [10] , [11] , [12] , [13] ] as well as with higher levels of proinflammatory biomarkers [ 14 ]. More recently, a prudent dietary pattern high in vegetables, potatoes, pasta, and rice, and low in refined cereals and sweetened beverages, was recently associated with the reduced risk of CDA in a small study on children [ 15 ].…”
Section: Introductionmentioning
confidence: 99%