Technology transfer is one of the facets of academic entrepreneurship and acts as a vital element of the innovation system. It forms a sustainable link between research and business communities. A holistic model for successfully transferring technology in developing countries is an unmet need in the context of technology transfer from public-funded academic research institutions to small and medium enterprises. In this work, we developed a conceptual model and undertook an empirical study for the determinants of successful transfer. A questionnaire was prepared and administered to key stakeholders involved in technology transfer. Overall, 321 respondents participated in the survey with congener demography. The conceptualized input factors, viz. micro-level, meso-level, and macro-level factors, are significantly interrelated. The contribution of input factors towards the successful transfer of technology was extensively analyzed and tested using covariance-based structural equation modeling. The results show that the model is a good fit. The study revealed that communication, innovativeness, knowledge, quality of the product, and motivation were the five most important factors for successfully transferring technology.