“…Following our experience with the first 7 patients,9 and in light of the fact that of the 9 patients who underwent transplantation between December 1999 and February 2003, 7 died and 3 were treated with DDI and/or d4T, whereas 1 died because of mitochondrial toxicity and a recurrence of HCV, we decided to avoid using nucleosides such as DDI and d4T analogs after LT and subsequently did not observe any lethal complications of HAART therapy during the post‐LT period. The avoidance of such complications, together with the transplantation of patients with lower MELD scores, will probably improve the survival of HCV‐HIV–coinfected patients 22–25…”
“…Following our experience with the first 7 patients,9 and in light of the fact that of the 9 patients who underwent transplantation between December 1999 and February 2003, 7 died and 3 were treated with DDI and/or d4T, whereas 1 died because of mitochondrial toxicity and a recurrence of HCV, we decided to avoid using nucleosides such as DDI and d4T analogs after LT and subsequently did not observe any lethal complications of HAART therapy during the post‐LT period. The avoidance of such complications, together with the transplantation of patients with lower MELD scores, will probably improve the survival of HCV‐HIV–coinfected patients 22–25…”
“…HIV/HBV-coinfected LT recipients seem to have better outcomes compared with those in HIV/HCV-coinfected liver transplant recipients as long as they receive early referral for LT and treatment of lamivudine-resistant HBV infection after LT (24,25).…”
HIV(+) patients without HCV coinfection seemed to have good prognosis, whereas patients who had HIV/HCV coinfection had poor outcomes, which were significantly worse than that seen in those with HCV alone.
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