2014
DOI: 10.1186/1756-0500-7-242
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The direct and indirect costs of both overweight and obesity: a systematic review

Abstract: BackgroundThe rising prevalence of overweight and obesity places a financial burden on health services and on the wider economy. Health service and societal costs of overweight and obesity are typically estimated by top-down approaches which derive population attributable fractions for a range of conditions associated with increased body fat or bottom-up methods based on analyses of cross-sectional or longitudinal datasets. The evidence base of cost of obesity studies is continually expanding, however, the sco… Show more

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Cited by 264 publications
(198 citation statements)
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“…Together, these data provide the first evidence that the VTA mediates the interaction of amylin and leptin to cooperatively promote negative energy balance. obesity; mesolimbic; reward; islet amyloid polypeptide OBESITY REPRESENTS A PREVALENT, COSTLY HEALTH PROBLEM in the US and worldwide (11,43,44), yet effective noninvasive treatment options for this disease are extremely limited. Many pharmacotherapeutic strategies to date have attempted to treat obesity by targeting a single feeding-related neuroendocrine system, but the vast majority of these monotherapy approaches have failed to produce meaningful and sustained reductions in body weight (41).…”
mentioning
confidence: 99%
“…Together, these data provide the first evidence that the VTA mediates the interaction of amylin and leptin to cooperatively promote negative energy balance. obesity; mesolimbic; reward; islet amyloid polypeptide OBESITY REPRESENTS A PREVALENT, COSTLY HEALTH PROBLEM in the US and worldwide (11,43,44), yet effective noninvasive treatment options for this disease are extremely limited. Many pharmacotherapeutic strategies to date have attempted to treat obesity by targeting a single feeding-related neuroendocrine system, but the vast majority of these monotherapy approaches have failed to produce meaningful and sustained reductions in body weight (41).…”
mentioning
confidence: 99%
“…La metodología permitió determinar el esfuerzo financiero adicional en la experiencia del cuidado de la salud desde la perspectiva de la familia discriminando los gastos que se asocian con servicios de salud de aquellos que se vinculan directamente al consumo familiar señalando que unos y otros hacen parte de la misma carga del cuidado [37][38][39] .…”
Section: Discussionunclassified
“…Después de la menopausia, cuando se suspende la producción de estrógeno ovárico, el tejido adiposo se convierte en la fuente principal de estrógeno endógeno a partir de precursores androgénicos. Mujeres postmenopáusicas obesas tienen mayores tasas de conversión de hormonas sexuales en comparación con mujeres postmenopáusicas no obesas (65,66). En general, las mujeres con niveles circulantes de estrógeno superiores al 20% de lo normal tienen entre 2 y 3 veces más riesgo de padecer cáncer (55,65).…”
Section: Figura 2 Mecanismos Biológicos De La Relación Entre Obesidaunclassified