The discovery and development of marine compounds with pharmaceutical potential

Antibiotic, cytotoxic and enzyme inhibitory activity of crude extracts from Brazilian marine invertebrates

“…Biological activities which have been frequently observed in marine invertebrate crude extracts include antibiosis against both human microbial pathogens and marine microorganisms (Slattery et al, 1997;Encarnación et al, 2000;Kuniyoshi and Higa, 2001) and cytotoxicity (reviewed in Garson, 1994;Cragg and Newman, 1999;Munro et al, 1999;Rinehart, 2000;Schmitz, 1994;Mayer, 1999;Mayer and Lehmann, 2001;Mayer and Hamann, 2002;Gustafson, 2003 andMayer et al, 2007). The fact that many marine invertebrate secondary metabolites have presented both antibiotic and cytotoxic activities is not only a consequence of their intrinsic activity, but also because research towards the search for new drugs has focused mainly on these bioassays (Newman et al, 2003).…”

Cultivation of Marine Sponges with Pharmaceutical Value: Status and Future Prospects in India

“…Sponges have potential as anti-cancer and anti-mitotic (Munro et al, 1999), antiprotozoal activity (Laport et al, 2009), antiviral and Ara-C (Arabinosysl Cytosine) -an anti-tumour compound marketed by Pharmacia & Upjohn Company in the brand name Cytosar-UR (Thakur and Muller, 2004). They also have potential anti-malarial, antimicrobial and cytotoxic properties (Pedpradab et al, 2010).…”

Recovery and Sequestration of Co2 From Stationary Combustion Systems by Photosynthesis of Microalgae

“…While such organisms offer advantages for the discovery phase, the availability of material needed for further testing may be very limited [27].…”