2020
DOI: 10.1101/2020.10.20.346882
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The domain-within-domain packing of euchromatin can be described as multiplicative cascades

Abstract: The genome is packed into the cell nucleus in the form of chromatin. Biochemical approaches have revealed that chromatin is packed within domains, which group into larger domains, and so forth. Such domain-within-domain packing, also called hierarchical packing, is equally visible in super-resolution microscopy images of large-scale chromatin organization. While previous work has suggested that chromatin is partitioned into distinct domains via microphase separation, it is unclear how these domains organize in… Show more

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