The donor notification process from the donor's perspective

Kleinman, Steven; Wang, Baoguang; Wu, Ying; Glynn, Simone A.; Williams, Alan G.; Nass, Catharie C.; Ownby, Helen E.; Busch, Michael P.

doi:10.1111/j.1537-2995.2004.03347.x

Cited by 44 publications

(71 citation statements)

References 8 publications

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“…Another drawback may be the relatively low response rate of surveyed donors. It did not differ, however, between FSUI and NI BDs and is essentially equivalent to that found by previous investigators who conducted mailed surveys of BDs 14,33 …”

Section: Discussionsupporting

confidence: 84%

Risk factors for hepatitis C virus infection among blood donors in Israel: a case‐control study between native Israelis and immigrants from the former Soviet Union

2007

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Section: Discussionsupporting

confidence: 84%

Risk factors for hepatitis C virus infection among blood donors in Israel: a case‐control study between native Israelis and immigrants from the former Soviet Union

2007

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“…Blood donor notification, counselling and referral clearly emerges as one of the single largest platform from where asymptomatic people could be informed of abnormal test results related to infectious agents that they could be harbouring silently today at least in the developing countries [13]. The early diagnosis of these infections facilitates institution of therapy in time which could result in prevention of significant morbidity and mortality in future, not to mention the cost of healthcare that could be prevented and quality of life that can be modified if they respond, and comply for follow up and management.…”

Section: Resultsmentioning

confidence: 99%

Risk Factors for Transfusion Transmissible Infections Elicited on Post Donation Counselling in Blood Donors: Need to Strengthen Pre-donation Counselling

Sachdev

Mittal

Patidar

et al. 2014

Indian J Hematol Blood Transfus

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Donor notification and counselling transforms the legal and ethical requirement of disclosure of transfusion transmissible infection (TTI) in a blood donor into practice. The present study was done to assess the response to the disclosure of TTI reactivity results in blood donors, assess the risk factors in blood donors and follow the compliance of the disclosure and clinical referral in a population of blood donors who are difficult to convince that they may be harbouring infections apparently in a healthy state today but with possible clinical disease consequences in the future. A retrospective study was conducted from April 2011 to November 2012. Screening was done using third generation ELISA kits used according to the manufacturer's directions; these kits were approved for use in blood banks by the Drug Controller General of India. Those testing repeat reactive were referred for further confirmation and management. The total number of TTI reactive donors was 787 (0.93 %, N = 83,865). The observed response rate in the present study is 21.6 % (167, N = 787). The risk factors for acquiring infections in TTI reactive donors were statistically significant history of high risk behaviour (20.3 %) for human immunodeficiency virus infection and history of jaundice in themselves, family or close contacts (16.1 %) for hepatitis B virus infection. One hundred and ten (65.8 %) of the referred donors were on outpatient clinical care when post-referral follow up was conducted. The study emphasises on continuing sensitization of blood donation camp organisers to the need of privacy during blood donor selection. The study also stresses the need to strengthen the pre-donation counselling at outdoor blood donation at the same time raise awareness amongst blood donors about the importance of postdonation counselling and follow up.

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“…76 The survey, which had a 42% response rate, documented that the majority of donors correctly understood their deferral status. However, about a quarter of donors did not, and confusion and emotional distress were reported by 81% and 75% of notified donors, respectively.…”

Section: The Domestic Research Program– Major Findingsmentioning

confidence: 99%

The National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Studies (Retrovirus Epidemiology Donor Study and Retrovirus Epidemiology Donor Study-II): Twenty Years of Research to Advance Blood Product Safety and Availability

Kleinman

King

Busch

et al. 2012

Transfusion Medicine Reviews

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The Retrovirus Epidemiology Donor Study (REDS), conducted from 1989–2001, and the Retrovirus Epidemiology Donor Study-II (REDS-II), conducted from 2004–2012, were National Heart Lung and Blood Institute (NHLBI) funded multicenter programs focused on improving blood safety and availability in the United States. REDS-II also included international study sites in Brazil and China. The three major research domains of REDS/REDS-II have been infectious disease risk evaluation, blood donation availability, and blood donor characterization. Both programs have made significant contributions to transfusion medicine research methodology by the use of mathematical modeling, large-scale donor surveys, innovative methods of repository sample storage, and establishing an infrastructure that responded to potential emerging blood safety threats such as XMRV. Blood safety studies have included protocols evaluating epidemiologic and/or laboratory aspects of HIV, HTLV I/II, HCV, HBV, WNV, CMV, HHV-8, B19V, malaria, CJD, influenza, and T. cruzi infections. Other analyses have characterized: blood donor demographics, motivations to donate, factors influencing donor return, behavioral risk factors, donors’ perception of the blood donation screening process, and aspects of donor deferral. In REDS-II, two large-scale blood donor protocols examined iron deficiency in donors and the prevalence of leukocyte antibodies. This review describes the major study results from over 150 peer-reviewed articles published by these two REDS programs. In 2011, a new seven year program, the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III), was launched. REDS-III expands beyond donor-based research to include studies of blood transfusion recipients in the hospital setting, and adds a third country, South Africa, to the international program.

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The donor notification process from the donor's perspective

Cited by 44 publications

References 8 publications

Risk factors for hepatitis C virus infection among blood donors in Israel: a case‐control study between native Israelis and immigrants from the former Soviet Union

Risk factors for hepatitis C virus infection among blood donors in Israel: a case‐control study between native Israelis and immigrants from the former Soviet Union

Risk Factors for Transfusion Transmissible Infections Elicited on Post Donation Counselling in Blood Donors: Need to Strengthen Pre-donation Counselling

The National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Studies (Retrovirus Epidemiology Donor Study and Retrovirus Epidemiology Donor Study-II): Twenty Years of Research to Advance Blood Product Safety and Availability

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