The Drs. Bergner Reply

Bergner, Arthur; Bergner, Renée K.

doi:10.1542/peds.58.1.137

Cited by 3 publications

(4 citation statements)

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“…Documented scientific investigations on garlic were initiated by Louis Pasteur who first reported its antibacterial and antifungal properties , . Albert Schweitzer used this concept and treated dysentery in Africa with garlic .…”

Section: Introductionmentioning

confidence: 99%

Freshly Crushed Garlic is a Superior Cardioprotective Agent than Processed Garlic

Mukherjee

Lekli

Goswami

et al. 2009

J. Agric. Food Chem.

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In this study, we compared the cardioprotective effects of freshly crushed garlic vis-à-vis that of processed garlic. Two groups of rats were gavaged with respective garlic preparations while the control group received vehicle only. After 30 days, all the rats were sacrificed and isolated hearts were subjected to 30 min ischemia followed by 2 h of reperfusion. Both the garlic preparations provided cardioprotection, but superior cardiac performance was noticed for those fed with freshly crushed garlic. Consistent with these results, freshly crushed garlic group displayed significantly greater phosphorylation of anti-apoptotic ERK1/2 proteins, reduced Bax/Bcl-2 ratio and reduced phosphorylation of proapoptotic p-38MAPK and JNK. Moreover, the survival signaling network consisting of Akt-FoxO1 was increased in the freshly crushed garlic treated hearts. Freshly crushed garlic, but not the processed garlic, showed enhanced redox signaling as evident by increased level of p65 subunit of NFκB, Nrf2 and enhanced GLUT 4, PPARα and PPARδ. The results thus show that although both freshly crushed garlic and processed garlic provide cardioprotection; the former has additional cardioprotective properties presumably due to the presence of H 2 S.

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Section: Introductionmentioning

confidence: 99%

Freshly Crushed Garlic is a Superior Cardioprotective Agent than Processed Garlic

Mukherjee

Lekli

Goswami

et al. 2009

J. Agric. Food Chem.

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“…Those predicates were considered minimized. Bergner [17] used this concept in his methodology for an ontology-driven product configuration process that covers both the definition and validation of the concepts and the subsequent configuration and hybrid validation of the product exemplars. "Hybrid" here means that the validation can be used according to the open-world assumption as well as according to the closed-world assumption.…”

Section: Process Engineering and Enactment Approachesmentioning

confidence: 99%

Semantically Valid Integration of Development Processes and Toolchains

Schramm

Andelfinger

Fischer

et al. 2022

Systems

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As an indispensable component of today’s world economy and an increasing success factor in production and other processes, as well as products, software needs to handle a growing number of specific requirements and influencing factors that are driven by globalization. Two common success factors in the domain of Software Systems Engineering are standardized software development processes and process-supported toolchains. Development processes should be formally integrated with toolchains. The sequence and the results of toolchains must also be validated with the specifications of the development process on several levels. The outcome of a conceptual deductive analysis is that there is neither a formal general mapping nor a generally accepted validation mechanism for the challenges that such an integrated concept faces. To close this research gap, this paper focuses on the core issue of the integration of development processes and toolchains in order to create benefits for modeling and automatization in the domain of systems engineering. Therefore, it describes a self-developed integration approach related to the recently introduced prototypical technical implementation TOPWATER. A unified metamodel specifies how processes and toolchains are linked by a general mapping mechanism that considers test options for the structural, content, and semantic levels.

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“…One of the foremost advantages of the present definition of psychopathology is that it provides a straightforward entree to integrating existing theoretical approaches to psychopathology and psychotherapy. A technical, highly systematic version of this integration has been given else-where (see Bergner, 1991a, 1991b). Due to limitations of space, and at the risk of appearing ad hoc, a highly condensed, nontechnical version will be sketched here.…”

Section: Entree To a Theoretical Integrationmentioning

confidence: 99%

“…It is also a paraphrase of the logic of many explanations from theories not ordinarily considered cognitive. For example, psychoanalytic “transference distortion” explanations and Rogerian “alienation from one's organismic valuing process” explanations are easily restated in cognitive deficit terms (see Bergner, 1991a, 1991b).…”

Section: Entree To a Theoretical Integrationmentioning

confidence: 99%

What is psychopathology? And so what?

Bergner¹

1997

Clinical Psychology: Science and Practice

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The present article comprises five parts. First, some serious consequences of our historical failure t o arrive at a consensus definition of psychopathology will be enumerated. Second, some general considerations regarding the nature of definitions will be reviewed.Third, a new definition of psychopathology will be presented and its adequacy justified in terms of its ability t o discriminate consensus cases of psychopathology from consensus noncases. Fourth, some importpnt advantages of this definition vis-i-vis its competitors will be noted; especially prominent here will be its provision of a straightforward enb& into an integration of existing theoretical approaches t o psychopathology and psychotherapy. Finally, some criticisms of other prominent definitions of psychopathology will be offered.

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The Drs. Bergner Reply

Cited by 3 publications

References 0 publications

Freshly Crushed Garlic is a Superior Cardioprotective Agent than Processed Garlic

Freshly Crushed Garlic is a Superior Cardioprotective Agent than Processed Garlic

Semantically Valid Integration of Development Processes and Toolchains

What is psychopathology? And so what?

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