The Dual Relationship Between Thymectomy and Autoimmunity

BCG and Autoimmunity: Another Two-Edged Sword

“…However, the mice that developed the SLE-like illness showed a significantly lower incidence of type I diabetes and amelioration of the pancreatic insulitis. This study's results are an example of the 'kaleidoscope phenomenon' [26][27][28][29][30] and they point to the importance of immune dysregulation in shift from one autoimmune disease to another-especially in individuals genetically prone to develop autoimmune conditions. One hypothesis offered to explain this manifestation is the 'common gene hypothesis'.…”