2024
DOI: 10.1101/2024.05.13.593821
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The dual resistance mechanism of CYP325G4 and CYP6AA9 inCulex pipiens pallenslegs according to transcriptome and proteome analysis

Yang Xu,
Jiajia Du,
Kewei Zhang
et al.

Abstract: Mosquitoes within the Culex pipiens complex play a crucial role in human disease transmission. Insecticides, especially pyrethroids, are used to control these vectors. Mosquito legs are the main entry point and barrier for insecticides to gain their neuronal targets. However, the resistance mechanism in mosquito legs is unclear. Herein, we employed transcriptomic analyses and isobaric tags for relative and absolute quantitation techniques to investigate the resistance mechanism, focusing on Cx. pipiens legs. W… Show more

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