In this paper we study inhomogeneous Diophantine approximation with rational numbers of reduced form. The central object to study is the set W (f, θ) as follows,for infinitely many coprime pairs of numbers m, n ,where {f (n)} n∈N and {θ(n)} n∈N are sequences of real numbers in [0, 1/2]. We will completely determine the Hausdorff dimension of W (f, θ) in terms of f and θ. As a by-product, we also obtain a new sufficient condition for W (f, θ) to have full Lebesgue measure and this result is closely related to the study of Duffin-Schaeffer conjecture with extra conditions.