1997
DOI: 10.1213/00000539-199701000-00028
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The Duration of Impairment of Autonomic Control After Anticholinergic Drug Administration in Humans

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Cited by 29 publications
(20 citation statements)
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“…The observed gradual diminution of the HF spectral component, RMSSD, pNN50 and SD1, as well as the proportional acceleration of heart rate during the glycopyrrolate infusion is consistent with previous reports on the effects of parasympathetic blockade on short‐term heart rate dynamics (Fouad et al ., 1984; Kamen et al ., 1996; Tulppo et al ., 1996; Parlow et al ., 1997; Scheinin et al ., 1999). Rigel et al .…”
Section: Discussionmentioning
confidence: 99%
“…The observed gradual diminution of the HF spectral component, RMSSD, pNN50 and SD1, as well as the proportional acceleration of heart rate during the glycopyrrolate infusion is consistent with previous reports on the effects of parasympathetic blockade on short‐term heart rate dynamics (Fouad et al ., 1984; Kamen et al ., 1996; Tulppo et al ., 1996; Parlow et al ., 1997; Scheinin et al ., 1999). Rigel et al .…”
Section: Discussionmentioning
confidence: 99%
“…Similarly, no statistically significant differences were found between patients with and without CAS‐D after CAS with respect to death, stroke, transient ischemic attack, or major adverse events in recently published analysis by Mylonas et al . In a large prospective study, Altinbas et al also found no significant association between the occurrence of either hemodynamic compromise or hypertension requiring treatment and the risk of stroke, MI, or death within 30 days from the intervention . Based on results of a prospective study following 223 patients, Cieri et al also concluded that even in severe CAS‐D there was no increased risk of adverse cerebrovascular or cardiac events .…”
Section: Clinical Significancementioning
confidence: 95%
“…1e5 There has been concern that anticholinergic drugs could induce ischaemia, possibly secondary to tachyarrhythmias, 4 5 and could pose a risk to patients with cardiovascular complications. 6 Among patients with congestive heart failure, SVT is a risk factor for stroke, as well as cardiovascular Key messages -Compared with LABA, tiotropium HandiHaler was associated with increased risks of angina, myocardial infarction and stroke and lower risk of total mortality. -The results of this study are similar to results from a recent clinical trial comparing tiotropium with salmeterol and support the hypothesis that tiotropium HandiHaler can be associated with an increased risk of ischaemic cardiovascular events.…”
Section: Introductionmentioning
confidence: 99%