According to the importance of fish farming in Egypt, this research was initiated with the objective of studying the parameter effected on economics of fish farming using water wells under several Egyptian conditions. In the primary phase of the study, the literature in the field of fish farming was assembled, reviewed, analysed, and categorized to deduce data about fish farming locations and to analyse such data. The research problem definition is concentrated in the lack of quantities of fish availability in Lake Qarun. Methodology is to identify many different variables such as the influence of environmental factors, water availability and water quality, the physical and chemical properties of water, climatic factors, fish death conditions, and weather in order to achieve the research objectives, which are to provide fish farming using surface well water as an accepted water quality for fish farming, to consider the soil as a filter for water and study the water quality from wells. This study was undertaken in Shakshouk Research Station of Fayoum governorate in Egypt during 2020 to 2022 to assess and evaluate the Tilapia Fish Farming Assessment using Water Wells in Fayoum governorate in Egypt. Based on the investigation outcomes, it was concluded that total direct and indirect cost comprised the capital and variable items of Egyptian pound (EGP). The cost of producing one kilogram of Tilapia fish was 25.4 EGP, and the selling price was 30 EGP for each kilogram of fish with markup including profit, risk contingency, financial charge, and market requirements for supply and demand all these items was estimated 4.6 EGP. This indicates that fish farming is a good way to take advantage of the enormous supply of water in the research station, and that it could be a substantial source of income in the case of increasing the awareness of regional people and an allocating a suitable market in the area.