The Dyspeptic Syndrome in Migraine: Morphofunctional Evaluation on 53 Patients

Centonze, Vincenzo; Polito, Beatrice Maria; Cassiano, M.; Doronzo, F.; Ricchetti, G.; Portincasa, Piero; Bassi, A.; Albano, O

doi:10.1046/j.1526-4610.1996.3607442.x

Cited by 9 publications

(13 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various gastrointestinal symptoms, such as nausea, vomiting, retching, and loss of appetite are characteristic of patients with migraine. In addition, migraine can be accompanied by a sense of heaviness in the epigastric region, epigastric pain, belching, and lower gastrointestinal symptoms, such as diarrhea and flatulence 2. The positive correlation between migraine and the presenece of symptoms consistent with functional gastrointestinal disorders (FGIDs) has previously been established in many clinical observations and epidemiological studies 2-6.…”

Section: Introductionmentioning

confidence: 98%

“…In addition, migraine can be accompanied by a sense of heaviness in the epigastric region, epigastric pain, belching, and lower gastrointestinal symptoms, such as diarrhea and flatulence 2. The positive correlation between migraine and the presenece of symptoms consistent with functional gastrointestinal disorders (FGIDs) has previously been established in many clinical observations and epidemiological studies 2-6. A recent large, population-based, cross-sectional study reported a higher prevalence of headache, including migraine, in individuals with reflux symptoms, diarrhea, constipation, or nausea than in individuals without such complaints 5.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Concomitant Functional Gastrointestinal Symptoms Influence Psychological Status in Korean Migraine Patients

Park¹,

Cho²,

Lee³

et al. 2013

Gut Liver

View full text Add to dashboard Cite

Background/AimsMigraine is frequently accompanied by symptoms consistent with functional gastrointestinal disorders (FGIDs). This study evaluated the prevalence of functional gastrointestinal symptoms and assessed the symptoms' relationship with the concomitant functional symptoms of anxiety, depression, and headache-related disability.MethodsThis prospective study included 109 patients with migraine who were recruited from a headache clinic at a teaching hospital. The participants completed a self-administered survey that collected information on headache characteristics, functional gastrointestinal symptoms (using Rome III criteria to classify FGID), anxiety, depression, and headache-related disability.ResultsIn total, 71% of patients met the Rome III criteria for at least one FGID. In patients with FGID, irritable bowel syndrome was the most common symptom (40.4%), followed by nausea and vomiting syndrome (24.8%) and functional dyspepsia (23.9%). Depression and anxiety scores were significantly higher in patients meeting the criteria for any FGID. The number of the symptoms consistent with FGID in individual patients correlated positively with depression and anxiety.ConclusionsFGID symptoms defined by the Rome III criteria are highly prevalent in migraine. These symptoms correlate with psychological comorbidities, such as depression and anxiety.

show abstract

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Concomitant Functional Gastrointestinal Symptoms Influence Psychological Status in Korean Migraine Patients

Park¹,

Cho²,

Lee³

et al. 2013

Gut Liver

View full text Add to dashboard Cite

show abstract

“…Migraine and headache are frequently reported by patients with gastrointestinal (GI) symptoms such as nausea, vomiting, retching, abdominal pain, and food intolerance 9-11. Among these symptoms, nausea and vomiting are the most common GI symptoms associated with migraine.…”

Section: Introductionmentioning

confidence: 99%

Clinical Predictors for Migraine in Patients Presenting With Nausea and/or Vomiting

Lee

et al. 2013

J Neurogastroenterol Motil

View full text Add to dashboard Cite

Background/AimsMany migraine patients develop nausea and/or vomiting (N/V) and are referred to gastroenterologists. This can lead to an inappropriate treatment and a delay of the correct diagnosis. We therefore aimed to identify predictors for migraine in patients presenting with N/V as well as headache.MethodsA total of 407 patients who were first diagnosed with migraine at Samsung Medical Center, Seoul, Korea, in 2009 were analyzed. Among them, 261 patients had N/V (migraine with N/V group) and 146 did not (migraine without N/V group). Each patient was evaluated using a structured questionnaire.ResultsMigraine with N/V group was younger, comprised of more females, had more abnormal body mass index, less alcohol intake, more family history of migraine, higher attack severity, more stress association, more aggravation by physical activity, more abdominal pain, and more photophobia/phonophobia than migraine without N/V group. Multivariate analysis revealed that young age (age < 40 years vs. ≥ 40 years, odds ratio (OR), 2.128; 95% confidence interval (CI), 1.206-3.756; P = 0.009), female (OR, 2.703; 95% CI, 1.492-4.896; P = 0.001), family history of migraine (OR, 2.080; 95% CI, 1.169-3.700; P = 0.013), abdominal pain (OR, 4.452; 95% CI, 1.263-15.693; P = 0.020), and photophobia/phonophobia (OR, 2.296; 95% CI, 1.308-4.030; P = 0.004) were independent predictive factors associated with migraine in patients with N/V.ConclusionsBecause young age, female, family history of migraine, abdominal pain, and photophobia/phonophobia are associated with migraine in patients presenting with N/V as well as headache, physicians should have a high index of suspicion for migraine in N/V patients who belong to these categories.

show abstract

“…Few studies are published on prevalence of endoscopic and gastrointestinal histopathologic findings among patients with migraine. 50 - 52 These studies reported a high prevalence of gastritis in the antrum or gastric corpus, and duodenitis among migraine sufferers. 50 - 52 The main problem in these studies is not excluding patients on analgesics.…”

Section: Discussionmentioning

confidence: 99%

“… 50 - 52 These studies reported a high prevalence of gastritis in the antrum or gastric corpus, and duodenitis among migraine sufferers. 50 - 52 The main problem in these studies is not excluding patients on analgesics. In our study, the endoscopic and pathologic findings were not statistically significant between migraine and non-migraine groups except for the presence of hiatal hernia.…”

Section: Discussionmentioning

confidence: 99%

Association of Gastrointestinal Functional Disorders and Migraine Headache: a Population Base Study

Lankarani¹,

Akbari²,

Tabrizi³

2017

Middle East J Dig Dis

View full text Add to dashboard Cite

BACKGROUND Migraine is one of the prevalent headaches. Many of patients with migraine, complain of gastrointestinal symptoms. There is limited studies on relation of gastrointestinal symptoms and migraine headache at population level. METHODS In this population-based study, 1038 subjects older than 15 year from a rural area in Fars province, south of Iran. were investigated for functional gastrointestinal disorders. By cluster random sampling, 160 of these persons invited to receive endoscopy along with histopathology samples of upper gastrointestinal tract. Data were analyzed using Pearson chi-square and Fisher exact. RESULTS Mean age of participations were 34.3 years with female to male of 3:1. The prevalence of migraine, irritable bowel syndrome (IBS), reflux, and dyspepsia were 24.6%, 17.7%, 17.4%, and 32.1%, respectively. There were significant relationship between migraine and functional gastrointestinal diseases (odds ratio of association for migraine with IBS, reflux, and dyspepsia were 3.43, 1.68, and 1.68 with p-value < 0.001 for all). In endoscopic findings, only presence of hiatal hernia was associated significantly with migraine (p = 0.011). No histopathologic findings in antral or duodenal biopsies were associated with migraine. CONCLUSION In this population based study we found significant association between migraines and gastrointestinal functional disorders including IBS, reflux and dyspepsia. This may have implication in better management of patients with migraine headache.

show abstract

The Dyspeptic Syndrome in Migraine: Morphofunctional Evaluation on 53 Patients

Cited by 9 publications

References 4 publications

Concomitant Functional Gastrointestinal Symptoms Influence Psychological Status in Korean Migraine Patients

Concomitant Functional Gastrointestinal Symptoms Influence Psychological Status in Korean Migraine Patients

Clinical Predictors for Migraine in Patients Presenting With Nausea and/or Vomiting

Association of Gastrointestinal Functional Disorders and Migraine Headache: a Population Base Study

Contact Info

Product

Resources

About