The “Dysplastic Nevus” Conundrum: A Look Back, a Peek Forward

Stefanato, Catherine M.

doi:10.1159/000487924

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…One potential problem encountered when calculating concordance is the ambiguity among histopathologists, dermatologists, and GPs regarding classification of some lesions, particularly atypical naevus and melanoma-in-situ (one is benign and the other malignant) [ 32 ]. SCC-in-situ was categorised as pre-malignant and SCC as malignant, so clinician classification as the former and pathologist classification as the latter would be discordant; in practice, both diagnoses would be managed similarly.…”

Section: Discussionmentioning

confidence: 99%

Remote Skin Cancer Diagnosis: Adding Images to Electronic Referrals Is More Efficient Than Wait-Listing for a Nurse-Led Imaging Clinic

Jones

Jameson

Oakley

2021

Cancers

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We undertook a retrospective comparison of two teledermatology pathways that provide diagnostic and management advice for suspected skin cancers, to evaluate the time from referral to diagnosis and its concordance with histology. Primary Care doctors could refer patients to either the Virtual Lesion Clinic (VLC), a nurse-led community teledermoscopy clinic or, more recently, to the Suspected Skin Cancer (SSC) pathway, which requires them to attach regional, close-up, and dermoscopic images. The primary objective of this study was to determine the comparative time course between the SSC pathway and VLC. Secondary objectives included comparative diagnostic concordance, skin lesion classification, and evaluation of missed skin lesions during subsequent follow-up. VLC referrals from July to December 2016 and 2020 were compared to SSC referrals from July to December 2020. 408 patients with 682 lesions in the VLC cohort were compared with 480 patients with 548 lesions from the 2020 SSC cohort, matched for age, sex, and ethnicity, including histology where available. Median time (SD) from referral to receipt of teledermatology advice was four (2.8) days and 50 (43.0) days for the SSC and VLC cohorts, respectively (p < 0.001). Diagnostic concordance between teledermatologist and histopathologist for benign versus malignant lesions was 70% for 114 lesions in the SSC cohort, comparable to the VLC cohort (71% of 122 lesions). Referrals from primary care, where skin lesions were imaged with variable devices and quality resulted in faster specialist advice with similar diagnostic performance compared to high-quality imaging at nurse-led specialist dermoscopy clinics.

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Section: Discussionmentioning

confidence: 99%

Remote Skin Cancer Diagnosis: Adding Images to Electronic Referrals Is More Efficient Than Wait-Listing for a Nurse-Led Imaging Clinic

Jones

Jameson

Oakley

2021

Cancers

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“…Since the late 1970s "dysplastic" nevi have been known to be associated with increased risk of melanoma, especially if the patient has been diagnosed with dysplastic nevus syndrome (B-K mole syndrome). Unfortunately, nowadays the terms dysplastic nevus (DN) and dysplastic nevus syndrome are controversial, especially with regards to the histologic definition of DN and common lack of its correlation with the clinical picture [14][15][16]. What is more, there is insufficient research into the relation between dominant dermoscopic patterns including the patterns which are considered benign and the incidence of cutaneous melanoma.…”

Section: Introductionmentioning

confidence: 99%

Predictive value of global dermoscopic pattern in patients diagnosed with cutaneous melanoma

Podolec

Brzewski

Pirowska

et al. 2021

pdia

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Introduction Dermoscopy is one of the most commonly used methods in early diagnosis of melanoma. It is conducted to differentiate between benign and malignant patterns in melanocytic lesions. Aim To determine if there is a predominance of one dermoscopic pattern in patients with melanoma and if there is a significant difference in dominant global dermoscopic pattern in patients with cutaneous melanomas correlated with patients’ sex and the location of the primary tumor. Material and methods The study included 162 patients with prior diagnosis of cutaneous melanoma. Dermoscopic and videodermoscopic pictures and patient data were analyzed with regard to the pattern: reticular, globular, homogeneous and mixed pattern (two-component pattern; reticular-globular pattern) with central or peripheral globules and multicomponent (mixed – at least 3 types of structures in one nevus). Results The reticular pattern was significantly more prevalent in male patients (38.57%, 27 patients) in comparison to female patients (18.45%, 17 patients). We also found a statistically significant lower prevalence of reticular pattern in patients diagnosed with melanomas located on upper limbs. The homogeneous pattern was statistically significantly more prevalent in patients in whom primary tumors were located on the head and upper limbs. Conclusions Our study suggests that predominant complex patterns are more commonly observed in patients diagnosed with cutaneous melanoma, although there is a significant number of patients with predominant reticular and homogeneous patterns, which are not often associated with an increased risk of development of melanoma.

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The “Dysplastic Nevus” Conundrum: A Look Back, a Peek Forward

Cited by 2 publications

References 16 publications

Remote Skin Cancer Diagnosis: Adding Images to Electronic Referrals Is More Efficient Than Wait-Listing for a Nurse-Led Imaging Clinic

Remote Skin Cancer Diagnosis: Adding Images to Electronic Referrals Is More Efficient Than Wait-Listing for a Nurse-Led Imaging Clinic

Predictive value of global dermoscopic pattern in patients diagnosed with cutaneous melanoma

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