The Early Enzymatic Debridement and Grafting of Deep Dermal Burns to the Hand

Gant, Thomas D.

doi:10.1097/00006534-198008000-00001

Cited by 17 publications

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“…Wang et al (10), reporting the results of a 10‐year experience, recommended tangential excision for all patients with burn wounds of the hands, especially within the first week, whenever the general health status of the patient was suitable. Gant (11), on the other hand, reported the results of the enzymatic removal of soft eschar within the first 24 hours to be esthetically and functionally excellent in the long run.…”

Section: Discussionmentioning

confidence: 99%

Debridement via Collagenase Application in Two Neonates

Tıraş¹,

Erdeve²,

Karabulut

et al. 2005

Pediatric Dermatology

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Slow-healing wounds contain insufficient amounts of intrinsic collagenases to provide sufficient wound debridement, so that the use of products containing synergistic collagenases and proteases may be helpful. We report the successful use of collagenase clostridipeptidase A in two newborns, a premature infant with 3rd degree burns, and a term neonate with an extravasation necrosis caused by calcium gluconate. Surgical excision of necrotic tissue is a serious intervention and prolongs the duration of hospitalization. Enzymatic eschar removal may have an advantage over surgery especially in newborns with a high risk for surgery, with its possible complications, need for anesthesia, and perhaps for blood transfusion.

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