The economic burden of breast cancer in California

Max, Wendy; Sung, Hai‐Yen; Stark, Brad

doi:10.1007/s10549-008-0149-4

Cited by 40 publications

(38 citation statements)

References 7 publications

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“…This study follows patterns similar to a study by Max et al, 26 although the study was specific to California women with differences in age distribution and study population. Similarly, Bradley et al 27 used the human capital approach to ascertain the value of lost productivity attributable to premature death, although the findings from this study are not comparable because of differences in age groups and time spans.…”

Section: Discussionsupporting

confidence: 70%

Health and Economic Impact of Breast Cancer Mortality in Young Women, 1970–2008

Ekwueme¹,

Guy²,

Rim³

et al. 2014

American Journal of Preventive Medicine

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Background Breast cancer is the second-leading cause of cancer-related deaths among women aged <50 years. Studies on the effects of breast cancer mortality among young women are limited. Purpose To assess trends in breast cancer mortality rates among women aged 20–49 years, estimate years of potential life lost (YPLL), and the value of productivity losses due to premature mortality. Methods Age-adjusted rates and rate ratios (RRs) were calculated using 1970–2008 U.S. mortality data. Breast cancer mortality rates over time were assessed using Joinpoint regression modeling. YPLL was calculated using number of cancer deaths and the remaining life expectancy at the age of death. Value of productivity losses was estimated using the number of deaths and the present value of future lifetime earnings. Results From 1970 to 2008, the age-adjusted breast cancer mortality rate among young women was 12.02/100,000. Rates were higher in the Northeast (RR=1.03, 95% CI, 1.02–1.04). The annual decline in breast cancer mortality rates among blacks was smaller (−0.68%) compared with whites (−2.02%). The total number of deaths associated with breast cancer was 225,866, which accounted for an estimated 7.98 million YPLL. The estimated total productivity loss in 2008 was $5.49 billion and individual lifetime lost earnings were $1.10 million. Conclusions Considering the effect of breast cancer on women of working age and the disproportionate impact on black women, more age-appropriate interventions with multiple strategies are needed to help reduce these substantial health and economic burdens, improve survival, and in turn reduce productivity costs associated with premature death.

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Section: Discussionsupporting

confidence: 70%

Health and Economic Impact of Breast Cancer Mortality in Young Women, 1970–2008

Ekwueme¹,

Guy²,

Rim³

et al. 2014

American Journal of Preventive Medicine

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“…Indeed, the economic impact of breast cancer is high [23-25]. The overall cost of managing local breast cancer was not significantly modified by the new organization, estimated at around €3,500.…”

Section: Discussionmentioning

confidence: 99%

Organizing medical oncology care at a regional level and its subsequent impact on the quality of early breast cancer management: a before-after study

Voidey

Pivot

Woronoff³

et al. 2014

BMC Health Serv Res

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BackgroundOne of the main measures of the French national cancer plan is to encourage physicians to work collectively, and to minimize territorial inequities in access to care by rethinking the geographical distribution of oncologists. For this reason, cancer care services are currently being reorganized at national level. A new infrastructure for multidisciplinary cancer care delivery has been put in place in our region. Patients can receive multidisciplinary health care services nearer their homes, thanks to a mobile team of oncologists. The objective of our study was to assess, using a quality approach, the impact on medical management and on the costs of treating early breast cancer, of the new regional structure for cancer care delivery.MethodsBefore-and-after study performed from 2007 to 2010, including patients treated for early breast cancer in three hospitals in the region of Franche-Comté in Eastern France. The main outcome measures were quality criteria, namely delayed treatment (>12 weeks), dose-intensity and assessment of adjuvant chemotherapy. Other outcomes were 24-month progression-free survival (PFS) and economic evaluation.ResultsThis study included 667 patients. The rate of chemotherapy tended to decrease, but not significantly (49.3% before versus 42.2% after, p=0.07), while the use of taxanes increased by 38% across all centres (59.6% before versus 98.0% after, p < 0.0001). There was a non-significant reduction in the time between surgery and adjuvant chemotherapy (6.0 ± 3.0 weeks before versus 5.6 ± 3.6 weeks after, p=0.11). Dose-dense chemotherapy improved slightly, albeit non significantly (86.3% versus 91.1% p=0.22) and time to treatment tended to decrease. The new regional infrastructure did not change 24-month PFS, which remained at about 96%. The average cost of treatment was estimated at €7000, with no difference between the two periods.ConclusionsDespite a shortage of oncologists, the new organization put in place in our region for the provision of care for early breast cancer makes it possible to maintain local community-based treatment, without negative economic consequences. This new structure for cancer care delivery offers cancer services of similar quality with no modification of 24-month PFS in early breast cancer.

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“…Most of the previously published research [11][12][13] estimated the average costs for women with and without breast cancer, whereas ours focused on the incremental cost impact. By comparing the costs of breast cancer patients with controls, we estimated the incremental costs related to breast cancer, netting out the indirect costs associated with socio-demographic factors and other comorbid conditions, which is more useful from an economic perspective.…”

Section: Discussionmentioning

confidence: 99%

“…For example, a recent study using the human capital approach projected that the value of lost productivity attributable to death from breast cancer in the US in 2010 will be $10.9 billion [11]. Another study estimated the economic burden of breast cancer in California [12] and showed that the value of lost productivity from premature deaths in 2001 cost the state of California $1.15 billion, whereas the direct health care cost was $279 million.…”

Section: Introductionmentioning

confidence: 99%

Absenteeism and short-term disability associated with breast cancer

Chen

Sullivan

et al. 2011

Breast Cancer Res Treat

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Few data exist related to the impact of breast cancer on work absenteeism and short-term disability. This retrospective study estimated the extent and costs of breast cancer-associated production loss using a large medical and pharmacy claims database from a US commercially insured population between January 2003 and December 2007. Women aged ≥ 18 years with ≥ 2 breast cancer diagnoses within 90 days were selected. Controls were matched to cases based on index date (first breast cancer diagnosis), age, region, employer, and health insurance type. Outcomes were days absent from work and days with short-term disability. Costs were estimated using daily wage rates. 856 and 2,668 patients were selected for absenteeism and short-term disability, respectively, with a mean age of 49 and 50 years. Average number of absenteeism days was 35 and 21, and short-term disability days were 51 and 5, for cases and controls, respectively, within the post-index year (both P < 0.001). Adjusted incremental costs for absenteeism and short-term disability were $1,911 and $6,157 (P < 0.001), respectively, per breast cancer patient per year. This study suggests that breast cancer is associated with work-related productivity loss within the first year of diagnosis that may be a substantial cost to employers.

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The economic burden of breast cancer in California

Cited by 40 publications

References 7 publications

Health and Economic Impact of Breast Cancer Mortality in Young Women, 1970–2008

Health and Economic Impact of Breast Cancer Mortality in Young Women, 1970–2008

Organizing medical oncology care at a regional level and its subsequent impact on the quality of early breast cancer management: a before-after study

Absenteeism and short-term disability associated with breast cancer

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