The effect of 1800 MHz radio-frequency radiation on NMDA receptor subunit NR1 expression and peroxidation in the rat brain in healthy and inflammatory states

Manmade Electromagnetic Fields and Oxidative Stress—Biological Effects and Consequences for Health

“…With respect to health effects, they are less conclusive, especially if no data are available on whether the observed effects are temporary or persistent. Nevertheless, most of the studies indicate changes in ROS formation and/or oxidative stress biomarkers [35,[40][41][42][43][44][45][46], examining and demonstrating morphological changes of the brain tissue in some cases [35,42,43,[46][47][48]. The study by Kesari et al described an increase in ROS formation and an elevation of oxidative stress markers, a marked reduction of antioxidative markers, and increased apoptosis rates in the brain of Wistar rats exposed daily for 2 h to 900 MHz RF-EMF for 45 days (pulsed at 217 Hz; SAR: 0.9 W/kg) [49].…”

“…In part, the changes in redox balance were accompanied by morphological changes that resemble those in neurodegenerative diseases [34,35,42,43,[46][47][48]53]. In general, studies, in which ROS, antioxidative markers, learning behavior, and memory performance were examined, suggest an impairment of neuronal functions of the animals.…”