The effect of 5A nursing combined with psychological nursing on the immune function, cancer-related fatigue and complications of patients undergoing radical resection of colorectal cancer

Xu, Yun; Yang, Juan

doi:10.14715/cmb/2022.68.1.21

Cited by 4 publications

(1 citation statement)

References 16 publications

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“…As a kind of tissue that can promote venous and lymphatic reflux, the respiratory muscle can regulate the left ventricular after-load hemodynamic index and improve cardiac autonomic tension (19). Therefore, by adding nursing measures such as respiratory training, res- piratory exercise (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30) and passive joint activity training of limbs in cardiopulmonary rehabilitation nursing, it is possible to effectively improve pulmonary hemodynamic indexes and reduce the risk of prognostic MACE.…”

Section: Discussionmentioning

confidence: 99%

The Effectiveness of Bax/Bcl-2 Gene Expression Ratio, Cardiac Function and Pulmonary Hemodynamics Indexes caused by Cardiopulmonary Rehabilitation Nursing

Luo¹,

Li²,

Li³

2022

Cell Mol Biol (Noisy-le-grand)

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This study aimed to observe the effects of cardiopulmonary rehabilitation nursing on gene expression, cardiac function and pulmonary hemodynamic indexes after percutaneous coronary intervention (PCI). A total of 104 coronary heart disease patients who received PCI treatment from January 2020 to January 2022 were selected by convenience sampling method. The patients were divided into control and observation groups by random number table method, with 52 cases in each group. The control group received routine nursing and the observation group received cardiopulmonary rehabilitation nursing. Cardiac function and pulmonary hemodynamics indexes were compared between the two groups. To evaluate gene expression, blood was taken from patients and healthy people after receiving complete information and obtaining consent. White blood cells were isolated by salting out. After RNA extraction and cDNA synthesis, the expression levels of Bcl2 and BAX genes were quantitatively measured by real-time PCR. Results showed that one month after discharge, the left ventricular end-diastolic diameter was decreased in the observation group compared with the control group and left ventricular ejection fraction and six minutes walk test grading were increased compared with the control group, showing a significant difference (P< 0.05). The pulmonary hemodynamic indexes were decreased in both groups compared with those at admission, but the pulmonary diastolic blood pressure, pulmonary systolic blood pressure, mean pulmonary artery pressure and pulmonary vascular resistance were lower in the observation group than in the control group of the same period, showing a difference (P< 0.05). The incidence of MACE was 1.92% (1/52) in the observation group, which was lower compared to the control group, showing a difference (P< 0.05). In this study, real-time PCR analysis showed that the expression ratio of Bcl2 to BAX genes in peripheral blood T cells in disease patients compared to healthy people was not different (P=0.07). In conclusion, Cardiopulmonary rehabilitation nursing for coronary heart disease after PCI can promote faster recovery of cardiac function, prolong exercise endurance and improve pulmonary hemodynamics indexes, demonstrating clinical reference value.

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Section: Discussionmentioning

confidence: 99%

The Effectiveness of Bax/Bcl-2 Gene Expression Ratio, Cardiac Function and Pulmonary Hemodynamics Indexes caused by Cardiopulmonary Rehabilitation Nursing

Luo¹,

Li²,

Li³

2022

Cell Mol Biol (Noisy-le-grand)

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MiR-485-3p/MiR-543/MiR-337-3p is Required for the Oncogenic Potential of the Hsa_circ_0007385-MEMO1 Axis in Colorectal Cancer

2023

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Influence of humanistic care-based operating room nursing on safety, recovery, and satisfaction after radical surgery for colorectal carcinoma

Wang,

Niu

2024

World J Clin Cases

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BACKGROUND Radical surgery is a preferred treatment for colorectal carcinoma, wherein nursing intervention is essential for postoperative recovery and prevention of complications. Recently, the application of humanistic care in medical care has attracted attention. Humanistic care emphasizes comprehensive care, with importance attached to patients’ physical needs as well as psychological and emotional support to provide more humane and personalized care services. However, no clinical reports have examined the use of humanistic care in patients undergoing radical surgery for colorectal carcinoma. AIM To investigate the influence of humanistic care-based operating room nursing on the safety, postoperative recovery, and nursing satisfaction of patients who have undergone radical surgery for colorectal carcinoma. METHODS In total, 120 patients with rectal cancer who underwent surgery in Zhongnan Hospital of Wuhan University between August 2023 and March 2024 were selected and grouped based on the nursing methods employed. Of these patients, 55 were treated with routine nursing intervention (control group) and 65 were provided humanistic care-based operating room nursing (research group). The patients’ vital signs were recorded, including systolic/diastolic blood pressure (SBP/DBP) and heart beats per minute (BPM), as well as serum stress indices, including norepinephrine (NE), adrenal hormone (AD), and cortisol (Cor). Postoperative recovery and complications were also recorded. Patients’ negative emotions, life hope, and nursing satisfaction were evaluated using the Self-rating Depression/Anxiety Scale (SDS/SAS), Herth Hope Index (HHI), and self-developed nursing satisfaction questionnaire, respectively. RESULTS During emergence from anesthesia, SBP, DBP, and BPM levels were found to be lower in the research group than those in the control group, also serum Cor, AD, and NE levels were lower. In addition, the research group had shorter operative, awakening, anal exhaust, first postoperative ambulation, drainage tube removal, intestinal recovery, and hospital times. The total complication rate and the SDS and SAS scores were lower in the research group than those in the control group. The HHI and nursing satisfaction scores were higher in the research group. CONCLUSION Humanistic care-based operating room nursing can mitigate physiological stress responses, reduce postoperative complications, promote postoperative recovery, relieve adverse psychological emotions, and enhance life hope and nursing satisfaction in patients undergoing radical surgery for colorectal carcinoma, which can be popularized in clinical practice.

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The effect of 5A nursing combined with psychological nursing on the immune function, cancer-related fatigue and complications of patients undergoing radical resection of colorectal cancer

Cited by 4 publications

References 16 publications

The Effectiveness of Bax/Bcl-2 Gene Expression Ratio, Cardiac Function and Pulmonary Hemodynamics Indexes caused by Cardiopulmonary Rehabilitation Nursing

The Effectiveness of Bax/Bcl-2 Gene Expression Ratio, Cardiac Function and Pulmonary Hemodynamics Indexes caused by Cardiopulmonary Rehabilitation Nursing

MiR-485-3p/MiR-543/MiR-337-3p is Required for the Oncogenic Potential of the Hsa_circ_0007385-MEMO1 Axis in Colorectal Cancer

Influence of humanistic care-based operating room nursing on safety, recovery, and satisfaction after radical surgery for colorectal carcinoma

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