The Effect of a Cation Exchange Resin on Electrolyte Balance and Its Use in Edematous States

Suppression of Sodium Excretion by the Colon in Congestive Heart Failure and Cirrhosis of the Liver Demonstrated by the Use of Cation Exchange Resins 1

“…It is, however, difficult to document a decrease in the excretion of fecal sodium because the amount of fecal sodium is normally quite small and variable (10). In order to insure sufficient amounts of sodium in the stool to be able to quantify a difference between the normal individual and the edematous patient, a cation exchange resin was fed (11). For proper interpretation of the data, the mechanics of the action of the resin in relation to sodium in the lumen of the gut must be considered (7).…”

Potentiation of Diuretic Action of Mercuhydrin by Ammonium Chloride 12

“…Against this is the observed potentiation of mercurial diuresis in edematous patients receiving cation exchange resins (18). These resins produce a deficit of fixed base in the extracellular fluid, and thereby cause an acidosis which when compensated is characterized by either normal or increased plasma chloride concentrations (18,19). In any event, however, it is extremely unlikely that increases in total body chloride content occur under these conditions.…”

Resinas Trocadoras De Cátions Na Hipercalemia Aguda Grave

“…A partir de 1935 foram desenvolvidas resinas com a capacidade de remover cátions ou ânions de soluções variadas, para uso industrial, e posteriormente para modificações no solo e abrandamento da água. O uso clínico se iniciou em 1945, quando foram usadas resinas trocadoras de íons no tratamento da úlcera péptica 2 . Em 1949, uma resina trocadora de cátions foi utilizada para remover sódio de pacientes com insuficiência cardíaca, e durante este estudo, observouse aumento da excreção fecal de potássio e redução da calemia 2 .…”