The effect of a combined HeNe and i.r. laser treatment on the regeneration of the lymphatic system during the process of wound healing

Lymphedema and breast cancer: a review of the literature

“…-Low level laser therapy uses low intensity at wavelengths between 650-1000 nm, either in a scanning or spot laser form. Research suggests that laser therapy increases the rate of lymph vessel pumping and promotes lymph vessel regeneration [51], reduces pain [52], and softens both fibrous tissue and surgical scarring [53]. -Compression bandaging consists of a gauze sleeve which protects the skin, soft cotton wrap or high density foam, and 2 or 3 layers of short-stretch bandaging.…”

Efficacy of 904 nm gallium arsenide low level laser therapy in the management of chronic myofascial pain in the neck: A double‐blind and randomize‐controlled trial

“…While the underlying mechanism is unknown, it has been demonstrated in animal studies that pulsed Nd-Yag laser therapy results in a selective reduction of A d and C fiber activity [32]. Anti-inflammatory effects have been demonstrated both in-vitro (820 nm Ga-Al-As) [33] and in-vivo (632.8 nm HeNe) [34] and a direct effect on motoricity of lymph vessels (630 nm He-Ne) [35], reducing interstitial fluid at the site of inflammation, has been described. Many investigators have observed an anti-inflammatory effect of LLLT in studies conducted in patients with rheumatoid arthritis by 10 Hz Q-switch neodymium laser (1.06 mm with an output of 15 J/cm 2 per 30 nanoseconds) [36] and by 630 nm He-Ne laser [37].…”

Effect of low-level laser therapy on pain and swelling in women with breast cancer-related lymphedema: a systematic review and meta-analysis

“…The proposed mechanisms involve cellularlevel changes in response to photon absorption, including alteration of membrane and organelle function and promotion of other reactions that initiate complex sequences of cellular response to aid tissue healing. In early studies on wound healing in mice, Lievens reported acceleration of both vein and lymph vessel regeneration with laser application [12,13]. More recently, LLLT was found to decrease the expression of profibrotic transforming growth factor and type I collagen deposition in the rat tibialis anterior muscle after muscle lesion, suggesting that LLLT may be helpful in preventing tissue fibrosis [14].…”