The effect of active surveillance for vancomycin-resistant enterococci in high-risk units on vancomycin-resistant enterococci incidence hospital-wide

Siddiqui, Anwer H.; Harris, Anthony D.; Hebden, Joan N.; Wilson, P. David; Morris, J. Glenn; Roghmann, Mary-Claire

doi:10.1067/mic.2002.118616

Cited by 49 publications

(26 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These projections are also compatible with the results of existing clinical studies, most of which have found that active surveillance can reduce VRE transmission in a variety of ICU environments and patient populations [13][14][15][16][17][18]. In addition, [19,20]. Despite such data, active surveillance for VRE has not been adopted by most health care institutions, and the rate of isolation of VRE has continued to increase as a percentage of all enterococcal clinical isolates [21].…”

Section: Discussionsupporting

confidence: 74%

Projected Benefits of Active Surveillance for Vancomycin‐Resistant Enterococci in Intensive Care Units

Perencevich¹,

Fisman²,

Lipsitch³

et al. 2004

CLIN INFECT DIS

View full text Add to dashboard Cite

Hospitals use many strategies to control nosocomial transmission of vancomycin-resistant enterococci (VRE). Strategies include "passive surveillance," with isolation of patients with known previous or current VRE colonization or infection, and "active surveillance," which uses admission cultures, with subsequent isolation of patients who are found to be colonized with VRE. We created a mathematical model of VRE transmission in an intensive care unit (ICU) using data from an existing active surveillance program; we used the model to generate the estimated benefits associated with active surveillance. Simulations predicted that active surveillance in a 10-bed ICU would result in a 39% reduction in the annual incidence of VRE colonization when compared with no surveillance. Initial isolation of all patients, with withdrawal of isolation if the results of surveillance cultures are negative, was predicted to result in a 65% reduction. Passive surveillance was minimally effective. Using the best available data, active surveillance is projected to be effective for reducing VRE transmission in ICU settings.

show abstract

Section: Discussionsupporting

confidence: 74%

Projected Benefits of Active Surveillance for Vancomycin‐Resistant Enterococci in Intensive Care Units

Perencevich¹,

Fisman²,

Lipsitch³

et al. 2004

CLIN INFECT DIS

View full text Add to dashboard Cite

show abstract

“…One hundred three of 2649 (3.9%) patients admitted during the study period acquired MRSA or VRE or both while on the BTU: MRSA (27), VRE (54), and both VRE and MRSA (13). Two patients' medical records were missing and four patients could not be matched to suitable controls.…”

Section: Resultsmentioning

confidence: 99%

“…Some investigators have shown that infection control strategies, such as screening all patients on admission and preemptively placing patients in contact precautions until their tests results are negative, cohorting patients infected or colonized with resistant organisms, and implementing alcohol-based hand sanitizers can decrease horizontal transmission of MRSA or VRE as well as the incidence of HAIs caused by these organisms. [22][23][24][25][26][27][28] However, these infection control measures have not been universally effective. For example, some investigators did not reduce the incidence of MRSA HAIs by introducing active screening for MRSA.…”

Section: Discussionmentioning

confidence: 97%

Risk Factors for Acquiring Vancomycin-Resistant Enterococcus and Methicillin-Resistant Staphylococcus aureus on a Burn Surgery Step-Down Unit

Wibbenmeyer

Williams

Ward

et al. 2010

Journal of Burn Care & Research

View full text Add to dashboard Cite

The incidence of hospital-associated infections secondary to methicillin-resistant Staphylococcus aureus (MRSA) and those caused by vancomycin-resistant enterococci (VRE) continue to increase, despite the publication of evidence-based guidelines on infection control. We sought to determine modifiable risks factors for acquisition of MRSA or VRE or both on a burn trauma unit (BTU). We performed a retrospective single-center-matched control study. Our study group comprised 94 patients who acquired MRSA or VRE or both while on the BTU from January 1, 2001 to December 31, 2005. The case-patients were matched 1:1 to control-patients based on the time the cases were exposed to the BTU before they became colonized or infected. Logistic regression was used to analyze the relationship of demographic, procedure, and antimicrobial exposure variables to acquisition of MRSA or VRE. Acquisition of MRSA or VRE was related to patient factors, antimicrobial exposure, and device use. Younger age and prior vancomycin treatment while on the BTU were independently associated with MRSA acquisition. The presence of a Foley catheter was related to VRE acquisition. Sixteen study patients (17.0%) who became colonized on the BTU subsequently acquired 17 infections: six patients had MRSA bloodstream infections, nine had MRSA burn wound infections, and two had VRE urinary tract infections. Younger age, exposure to vancomycin, or Foley catheters were associated with increased risk of acquiring MRSA or VRE. Protocols or algorithms that help physicians remember to assess the necessity of antimicrobial agents and devices may help limit the duration of exposure to these risk factors, which may enhance infection prevention efforts. Future studies need to explore the effect of these variables on cross-transmission and their impact predominately in a burn unit.

show abstract

“…62,63 Active surveillance may reduce transmission of MDR organisms when performed in high-risk patient care units. 64 Surveillance cultures for MRSA, VRE and other MDR gram negative bacteria can be obtained from skin, nasal and rectal swabs, or stool samples.…”

Section: Microbiological Detection Of Bloodstream Infections In Hct Pmentioning

confidence: 99%

Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis

Dandoy

Ardura

Papanicolaou

et al. 2017

Bone Marrow Transplant

View full text Add to dashboard Cite

Bacterial bloodstream infections (BSI) cause significant transplant-related morbidity and mortality following allogeneic hematopoietic cell transplantation (allo-HCT). This manuscript reviews the risk factors for and the bacterial pathogens causing BSIs in allo-HCT recipients in the contemporary transplant period. In addition, it offers insight into emerging resistant pathogens and reviews clinical management considerations to treat and strategies to prevent BSIs in allo-HCT patients.

show abstract

The effect of active surveillance for vancomycin-resistant enterococci in high-risk units on vancomycin-resistant enterococci incidence hospital-wide

Cited by 49 publications

References 9 publications

Projected Benefits of Active Surveillance for Vancomycin‐Resistant Enterococci in Intensive Care Units

Projected Benefits of Active Surveillance for Vancomycin‐Resistant Enterococci in Intensive Care Units

Risk Factors for Acquiring Vancomycin-Resistant Enterococcus and Methicillin-Resistant Staphylococcus aureus on a Burn Surgery Step-Down Unit

Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis

Contact Info

Product

Resources

About