The Effect of Acupuncture on the Motor Function and White Matter Microstructure in Ischemic Stroke Patients

Li, Yongxin; Wang, Ya; Zhang, Heye; Wu, Ping; Huang, Wenhua

doi:10.1155/2015/164792

Cited by 19 publications

(15 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A recent DTI study showed that a 4-week acupuncture treatment with conventional medication could improve the FMA score and white matter diffusion parameters compared to medication alone in stroke patients with unilateral motor deficits [55]. Thus, the lack of clear-cut different results between the RT + CT group and CT group in this study may have been obscured by the potential therapeutic effect of acupuncture present in both treatment groups, or the greater improvement in FMA score in the RT + CT group may still reflect additional beneficial effects of rTMS over CT on motor recovery.…”

Section: Discussionmentioning

confidence: 99%

Ipsilesional High Frequency Repetitive Transcranial Magnetic Stimulation Add-On Therapy Improved Diffusion Parameters of Stroke Patients with Motor Dysfunction: A Preliminary DTI Study

et al. 2016

View full text Add to dashboard Cite

Purpose. The aim of this study was to evaluate the effects of high frequency repetitive transcranial magnetic stimulation (HF-rTMS) on stroke patients with motor dysfunction and to investigate the underlying neural mechanism. Methods. Fifteen stroke patients were assigned to the rTMS treatment (RT) group and conventional treatment (CT) group. Patients in the RT received 10 Hz rTMS stimulation on the ipsilesional primary motor cortex for 10 days plus conventional treatment of CT, which consisted of acupuncture and antiplatelet aggregation medication. Difference in fractional anisotropy (FA) between pretreatment and posttreatment and between two groups was determined. Correlations between FA values and neurological assessments were also calculated. Results. Both groups significantly improved the neurological function after treatment. rTMS-treated patients showed better improvement in Fugl-Meyer Assessment (FMA) score and increased FA value in motor-related white matter and gray matter cortices compared with CT-treated patients and pretreatment status. Besides, the increased FA value in the ipsilesional posterior limb of the internal capsule in RT group was significantly correlated with the improved FMA score. Significance. HF-rTMS could be a supplement therapy to CT in improving motor recovery in patients with stroke. And this benefit effect may be achieved through modulating the ipsilesional corticospinal tracts and motor-related gray matter cortices.

show abstract

Section: Discussionmentioning

confidence: 99%

Ipsilesional High Frequency Repetitive Transcranial Magnetic Stimulation Add-On Therapy Improved Diffusion Parameters of Stroke Patients with Motor Dysfunction: A Preliminary DTI Study

et al. 2016

View full text Add to dashboard Cite

show abstract

“…First, acupuncture can directly enhance the motor function and daily life of stroke patients. Acupuncture has been shown to lead to a higher improvement in motor function than conventional treatment [23]. Acupuncture when combined with rehabilitation may have a positive effect on motor function, activity of daily life, neurological deficits, and spasticity [24].…”

Section: Total (95% Ci)mentioning

confidence: 99%

Acupuncture plus Rehabilitation for Unilateral Neglect after Stroke: A Systematic Review and Meta‐Analysis

Hou

Liu

et al. 2020

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Objectives. To systematically assess the efficacy of acupuncture combined with rehabilitation on unilateral neglect after stroke. Methods. The Cochrane Library, PubMed, Excerpt Medical Database (EMBASE), China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), Chinese Biomedical Literature Database (CBM), and Wan Fang databases were searched online for randomised controlled trials (RCTs) of acupuncture and its effects on unilateral neglect after stroke from their inception to September 2019. RCTs on acupuncture combined with rehabilitation in the experimental group for unilateral neglect compared with rehabilitation alone or rehabilitation plus sham acupuncture in the control group were included. Two authors separately screened the literature, extracted the data, and evaluated the quality of the included studies. Review Manager 5.3 software was used for the data analysis. Results. A total of 542 patients from nine RCTs were included. The meta-analysis showed that the experimental groups could significantly improve Fugl–Meyer Assessment (FMA) (MD = 11.54, 95% CI [9.54, 13.54], P<0.00001) and the ability of daily living (SMD = 1.35, 95% CI [0.64, 2.07], P<0.00001) when compared with the control groups. However, there was no significant difference in the drop of Catherine Bergego Scale (CBS) and Behavioural Inattention Test-conventional (BIT-C) between the two groups. Conclusions. Acupuncture combined with rehabilitation was more effective in improving the motor function and the ability of daily living. Because of the limitations regarding the quantity and quality of the studies in this meta-analysis, high-quality and well-designed RCTs are necessary to validate the above conclusions.

show abstract

“…Both SA and body acupuncture were used during clinical trials that reported positive effects of acupuncture for ischemic stroke [44,45].…”

Section: Analysis Of the Efficacy Of Sa For Patients With CImentioning

confidence: 99%

Synergistic effects of scalp acupuncture and repetitive transcranial magnetic stimulation on cerebral infarction: a randomized controlled trial

Kim

Han

Song

et al. 2019

Preprint

View full text Add to dashboard Cite

Background Presently, there is a need for stroke treatment strategies that combine multiple disciplines, such as neurology, rehabilitation medicine, and traditional medicine. This study investigated the synergistic effects of scalp acupuncture (SA) and repetitive transcranial magnetic stimulation (rTMS) known to be effective for cerebral infarction. Methods This outcome assessor-blinded randomized controlled clinical trial included a per-protocol analysis to compare the efficacy of SA and electromagnetic convergence stimulation (SAEM-CS), which comprises the simultaneous application of low-frequency rTMS, SA, rTMS, and conventional stroke rehabilitation therapy (CSRT) for cerebral infarction patients. The trial was completed by 42 cerebral infarction patients (control group, 12; SA group, 11; rTMS group, 8; SAEM-CS group, 11). All patient groups underwent two sessions of CSRT per day. SA, rTMS, and SAEM-CS were conducted once per day, 5 days per week, for 3 weeks. The primary outcome (motor function recovery) was evaluated using the Fugl‐Mayer assessment (FMA). Other scales were used to assess cognitive function, activities of daily living, walking, quality of life, and stroke severity, which were secondary outcomes. Results There were significant changes (week 7–week 0) between groups in the FMA upper extremity (FMAUE), FMA total (FMAT), modified Barthel index (MBI), and functional independent measurement (FIM) scores. There were no significant changes in the scores of other outcome measures. FMAUE (p=0.015), FMAT (p=0.023), MBI (p=0.002), and FIM (p<0.001) scores significantly increased in the rTMS group compared with the control group and FMAUE (p=0.016), FMAT (p=0.012), MBI (p=0.026), and FIM (p=0.012) scores significantly increased in the rTMS group compared with the SAEM-CS group. However, there were no significant changes in the SA or SAEM-CS group. Conclusions Low-frequency rTMS in the contralesional hemisphere had long-term therapeutic effects on upper extremity motor function recovery and on improvements in activities of daily living. SAEM-CS had no positive synergistic effects of SA and rTMS on motor function recovery, cognitive function, activities of daily living, walking, quality of life, and stroke severity. Trial Registration URL: cris.nih.go.kr. Unique identifier: KCT0001768, retrospectively registered (registration date: January 14, 2016).

show abstract

The Effect of Acupuncture on the Motor Function and White Matter Microstructure in Ischemic Stroke Patients

Cited by 19 publications

References 52 publications

Ipsilesional High Frequency Repetitive Transcranial Magnetic Stimulation Add-On Therapy Improved Diffusion Parameters of Stroke Patients with Motor Dysfunction: A Preliminary DTI Study

Ipsilesional High Frequency Repetitive Transcranial Magnetic Stimulation Add-On Therapy Improved Diffusion Parameters of Stroke Patients with Motor Dysfunction: A Preliminary DTI Study

Acupuncture plus Rehabilitation for Unilateral Neglect after Stroke: A Systematic Review and Meta‐Analysis

Synergistic effects of scalp acupuncture and repetitive transcranial magnetic stimulation on cerebral infarction: a randomized controlled trial

Contact Info

Product

Resources

About