“…For sequence generation, 7 studies (50.0%) were coded as unclear risk 25,27,29,30,33,34,37 while the other 7 (50.0%) were considered low risk 22,24,26,32,35,37,38 . With respect to allocation concealment, 8 studies (57.1%) were coded as being at an unclear risk of bias, 24,25,28,30,33–36 while the remaining 6 (42.9%) were considered low risk 22,26,27,31,32,37 . For blinding, 11 studies (78.6%) were coded as high risk of bias 22,25,27,30,32–38 , 2 (14.3%) were unclear 24,26 , and 1 (7.1%) was classified as low risk 31 .…”