The Effect of Adding Two Different Doses of Magnesium Sulphate as Adjuvant to Ropivacaine in Peribulbar Block for Cataract Surgery

Mogahed, Mona Mohamed; Anwar, Atteia Gad; Abo-elazm, Wessam Nassar

doi:10.4172/2155-6148.1000725

Cited by 3 publications

(2 citation statements)

References 28 publications

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“…Mogahed et al [ 23 ] compared two different doses of magnesium sulfate (50 or 100 mg) added to ropivacaine in peribulbar block. Although both doses caused a rapid onset and prolonged duration of sensory and motor blockade, but the results were more significant on using 100 mg of magnesium sulfate than 50 mg.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of magnesium sulfate as an adjuvant in sub-Tenon anesthesia for cataract surgery

Ahmad

Zahoor

Font³

et al. 2023

Saudi Journal of Anaesthesia

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Purpose: To evaluate the efficacy, safety, and satisfaction for the use of adjuvant; magnesium sulfate (MgSO 4 ) in sub-Tenon anesthesia for cataract surgery. Methods: This single centered randomized, double blind trial was held in 2021 after approval of ethical committee at the Eye Hospital, Riyadh, Saudi Arabia. Cataract patients to be operated using local anesthesia were randomly assigned to two groups; Group magnesium sulfate (MS) received 50 mg/0.5 ml of magnesium sulfate and Group normal saline (NS) received 0.5 ml of normal saline added to the standard mixture, respectively. Absence of eyelid dropping and akinesia of the globe at different time after anesthesia were considered as ineffective anesthesia. The age and sex-adjusted generalized estimating equation (GEE) analysis was carried out. Complications, patient's and surgeon's satisfaction were also compared. Results: Each group had 100 cataract patients. Effectiveness of block was not significantly different in two groups (adjusted odds ratio, 0.90; 95% confidence interval [CI], 0.62, 1.31; P = 0.594). The likelihood of “no eye-opening” significantly increased with time (adjusted odds ratio, 1.26; 95% CI, 1.18–1.34; P < 0.001). Subconjunctival bleeding was significantly higher in the MS versus NS Group (36 of 98 [36.7%] vs. 11 of 102 [10.8%], P < 0.001). Chemosis was not significantly different between the groups ( P = 0.95). Patient's satisfaction score was very good (9/10) but slightly higher in NS group than MS ( P = 0.001) while surgeon's satisfaction score was similar in both groups ( P = 0.149). Conclusions: Although safe, adding 50 mg of magnesium sulfate did not improve the effect of sub-Tenon anesthesia for cataract surgery. Risk of subconjunctival bleeding was higher in cataract patients operated using MgSO 4 compared to those managed with the conventional sub-Tenon anesthetic.

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Section: Discussionmentioning

confidence: 99%

Evaluation of magnesium sulfate as an adjuvant in sub-Tenon anesthesia for cataract surgery

Ahmad

Zahoor

Font³

et al. 2023

Saudi Journal of Anaesthesia

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“…Those outcomes were more huge with respect to utilizing 100 mg magnesium sulfate. [9]. S were as about rocuronium of the neighborhood analgesic mixture brings about a exceptional akinesia score Furthermore speedier foundation of suitableness states will begin waterfall surgery compared for the individuals in the magnesium Furthermore placebo aggregations [10].…”

Section: Discussionmentioning

confidence: 99%

Evalution of the Effect of Addition of Magnesium Sulfate to Local Anesthetics for Peribulbar Block: a Meta-Analysis for Randomized Trials

Hamid

Khashaba

Aboelsaod

2020

Benha Journal of Applied Sciences

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Efficacy of Addition of Magnesium as an Adjuvant to Local Anaesthetics in Peribulbar Block: A Prospective Randomized Double-Blind Study

Jamadar

Pasupuleti

2022

PIJR

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Introduction: Topical, regional or general anesthesia can be used for ocular surgery. Among regional blocks, Peribulbar block is a good choice as it provides efficient anesthesia with good lid and globe akinesia with low incidence of complications.1 However the time for onset of akinesia with Peribulbar block is much longer in comparison to retro bulbar block,2which may lead to a delay to start the surgery. The incidence of inadequate analgesia is also more frequent with Peribulbar block2 in comparison to retro bulbar block, which may lead to the requirement of supplementary injection before the start of surgery or intraoperatively. Aims And Objectives: To evaluate the effect of addition of magnesium sulphate to standard local anesthetics mixture for peribulbar blocks in ophthalmic surgeries. Material And Methods: 60 patients who underwent ocular surgery under local anesthesia admitted at Malla Reddy Narayana Multispecialty Hospital, Hyderabad from May2018- october2018(6 months) were enrolled in the study.It was Prospective Randomized controlled double blind study.Inclusion criteria was patients between 20-70 years of either sex with ASA group 1-3 with both anterior and posterior chamber surgery under peribulbar block.Exclusion criteria were patient with mental retardation, allergic to local anesthetics, history of bleeding disorder, cardiac and respiratory diseases and ASA group4-5. Results: After studying 60 patients, out of which 30 patients included in control group (Group NS) and 30 patients in study (Group MS) group,a systematic statistical analysis done for Age and All patients were in age group of 20-70 years. Mean age was 59.0667 +- 7.08049 in the control group (Group NS) and 58.1667 +- 5.73605 in study group (Group MS). The p-value 0.591,which is statistically nonsignificant. Discussion:Anaesthesia plays a vital role in ophthalmic surgery.Most ophthalmic surgeries are carried out under local anaesthesia although topical anaesthesia is soon gaining popularity.The goal of anaesthesia in opthalmic surgery is to provide adequate analgesia and akinesia.Peribulbar block has been used widely for ophthalmic surgery as it is safer than a retrobulbar block. The time for onset of akinesia with peribulbar block is much longer in comparison to retrobulbar block2, which may lead to a delay to start the surgery.The incidence of inadequate analgesia is also more frequent with peribulbar block2 in comparison to retrobulbar block, which may lead to the requirement of supplementary injection before the start of surgery or intraoperatively. Conclusions: Faster onset of globe and lid akinesia after addition of Magnesium sulphate to the mixture of local anaesthetics in peribulbar block.The duration of globe and lid akinesia is prolonged but difference is not statistically significant in Group MS as compared to Group NS.

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The Effect of Adding Two Different Doses of Magnesium Sulphate as Adjuvant to Ropivacaine in Peribulbar Block for Cataract Surgery

Abstract: Background: This study was designed to compare the effects of adding two different doses of magnesium sulphate to the local anesthesia during peribulbar block.

Cited by 3 publications

References 28 publications

Evaluation of magnesium sulfate as an adjuvant in sub-Tenon anesthesia for cataract surgery

Evaluation of magnesium sulfate as an adjuvant in sub-Tenon anesthesia for cataract surgery

Evalution of the Effect of Addition of Magnesium Sulfate to Local Anesthetics for Peribulbar Block: a Meta-Analysis for Randomized Trials

Efficacy of Addition of Magnesium as an Adjuvant to Local Anaesthetics in Peribulbar Block: A Prospective Randomized Double-Blind Study

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