Background. Sacroiliitis may be degenerative (DSI) or inflammatory (ISI) and the latter is a clinical manifestation of spondyloarthropathies. Objective. To determine the effect of hyaluronic acid versus corticosteroid injection for chronic sacroiliac joint arthropathy. Methods. Forty patients with sacroiliitis either degenerative (DSI: 20 patients) or inflammatory (ISI: 20 patients) based on the New York criteria. Each group was allocated into 2 subgroups; 10 patients received 2 ml betamethasone dipropionate plus 2 ml lidocaine 2% (A) and 10 patients received 2 ml hyaluronic acid plus 2 ml lidocaine 2% (B). All sacroiliac joint injections were done under ultrasonographic guidance using a 22-gauge needle. Visual analogue scale (VAS) was used for pain assessment at base line, 1-, 2-and 4-week post injection. Results. No significant difference was observed between main groups (ISI and DSI) regarding VAS score before injection, 1-, 2-and 4-weeks post injection while a significant difference observed between subgroups A and B in ISI group at 2 and 4 weeks (p = 0.012 and 0.008, respectively). Also, there was a significant difference between subgroups A and B in DSI group at 1-, 2-and 4-weeks post injection (p = 0.04, 0.006 and 0.005, respectively). High significant difference before and after injection in the main groups and all subgroups was recorded. However, there was no significant difference between the subgroups of ISI and DSI. Conclusions. Both steroid and hyaluronic acid were effective in relieving pain in treatment of inflammatory and degenerative sacroiliitis, but steroid was more efficacious than the hyaluronic acid. Study registration. The trial registration number is PACTR202111473947054 (www. pactr.org).