The Effect of Adenotonsillectomy on Mean Platelet Volume and Neutrophil-toLymphocyte Ratio

Abstract

Objectives:To explore the effect of adenotonsillectomy on mean platelet volume (MPV) levels and neutrophil to lymphocyte ratio (NLR) values in children with obstructive sleep apnea syndrome (OSAS). Subjects and Methods: In total, 127 children (69 males, 58 females; average age 10.20±8.96 years; range, 5-18 years) who underwent adenotonsillectomy with a diagnosis of OSAS were included in the study. Pre-operative MPV levels and NLR values were compared with measurements in the post-operative third month. A p-value <0.05 was considered to reflect statistical significance. Results: Mean pre-operative MPV values were 8.12±1.28 femtoliters (fL) and mean post-operative MPV values were 7.96±1.01 fL, respectively. Post-operative MPV values were significantly lower than pre-operative measurements (p=0,028, p<0.05). Mean pre-operative NLR levels were 1.46±0.82 and post-operative NLR values were 1.42±1.01, respectively. Post-operative NLR values were significantly lower than pre-operative NLR values (p=0.032, p<0.05). Conclusion: We observed statistically significant lower MPV levels and NLR values after adenotonsillectomy in children with OSAS. Future randomized studies should explore the relationship between the MPV levels, NLR values and parameters in polysomnography in larger numbers of patients with OSAS.