The Effect of Age and Gender on 38 Chemical Element Contents in Human Femoral Neck Investigated by Instrumental Neutron Activation Analysis

Zaichick, Sofia; Zaichick, Vladimir

doi:10.1007/s12011-009-8554-z

Cited by 50 publications

(48 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to Zaichick et al [29, 30, 43], ribs show higher contents of Cd, Ni and Cu, and the content of Zn in the tibia and the femur was at a similar level.…”

Section: Discussionmentioning

confidence: 99%

Factors that Affect the Content of Cadmium, Nickel, Copper and Zinc in Tissues of the Knee Joint

Roczniak

Brodziak-Dopierała

Cipora

et al. 2017

Biol Trace Elem Res

View full text Add to dashboard Cite

Osteoarthritis causes the degradation of the articular cartilage and periarticular bones. Trace elements influence the growth, development and condition of the bone tissue. Changes to the mineral composition of the bone tissue can cause degenerative changes and fractures. The aim of the research was to determine the content of cadmium (Cd), nickel (Ni), copper (Cu) and zinc (Zn) in the tibia, the femur and the meniscus in men and women who underwent a knee replacement surgery. Samples were collected from 50 patients, including 36 women and 14 men. The determination of trace elements content were performed by ICP-AES method, using Varian 710-ES. Average concentration in the tissues of the knee joint teeth amounted for cadmium 0.015, nickel 0.60, copper 0.89 and zinc 80.81 mg/kg wet weight. There were statistically significant differences in the content of cadmium, copper and zinc in different parts of the knee joint. There were no statistically significant differences in the content of cadmium, nickel, copper and zinc in women and men in the examined parts of the knee joint. Among the elements tested, copper and nickel showed a high content in the connective tissue (the meniscus) compared to the bone tissue (the tibia and the femur).

show abstract

“…According to Zaichick et al [29, 30, 43], ribs show higher contents of Cd, Ni and Cu, and the content of Zn in the tibia and the femur was at a similar level.…”

Section: Discussionmentioning

confidence: 99%

Factors that Affect the Content of Cadmium, Nickel, Copper and Zinc in Tissues of the Knee Joint

Roczniak

Brodziak-Dopierała

Cipora

et al. 2017

Biol Trace Elem Res

View full text Add to dashboard Cite

show abstract

“…In a human biomonitoring study, Zaichick and Zaichick [24–27] established physiological levels of Zn in the femoral head, iliac crest and rib among inhabitants of Central Europe: 58.1, 60.8, and 92.4 mg/kg dw, respectively while the physiological levels of Cu in the bone were deemed to be 5–6 mg/kg dw. The average concentration of Cu in samples of ribs from Russians ranged from 0.84 to 1.0 mg/kg dw [24, 26].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Metal Concentrations in Bones of Long-Living Mammals

Lanocha

Kalisińska

Kosik-Bogacka

et al. 2013

Biol Trace Elem Res

View full text Add to dashboard Cite

The aim of this study was to compare zinc, copper, lead, cadmium, and mercury concentrations in the bones of long-living mammals—humans (Homo sapiens) and Canidae (dogs Canis familiaris and foxes Vulpes vulpes) from northwestern Poland and to determine the usefulness of Canidae as bioindicators of environmental exposure to metals in humans. Zinc concentrations in cartilage with adjacent compact bone and in spongy bone were highest in foxes (∼120 mg/kg dry weight (dw)) and lowest in dogs (80 mg/kg dw). Copper concentrations in cartilage with adjacent compact bone were greatest in foxes (1.17 mg/kg dw) and smallest in humans (∼0.8 mg/kg dw), while in spongy bone they were greatest in dogs (0.76 mg/kg dw) and lowest in foxes (0.45 mg/kg dw). Lead concentrations in both analyzed materials were highest in dogs (>3 mg/kg dw) and lowest in humans (>0.6 mg/kg dw). Cadmium concentration, also in both the analyzed materials, were highest in foxes (>0.15 mg/kg dw) and lowest in humans (>0.04 mg/kg dw). Mercury concentration in bones was low and did not exceed 0.004 mg/kg dw in all the examined species. The concentrations of essential metals in the bones of the examined long-living mammals were similar. The different concentrations of toxic metals were due to environmental factors. As bone tissues are used in the assessment of the long-term effects of environmental exposure to heavy metals on the human body, ecotoxicological studies on the bones of domesticated and wild long-living mammals, including Canidae, may constitute a significant supplement to this research.

show abstract

“…15 Selenium is a minority element of biological tissues, being present in the body in amounts of less than 0.1% of body weight. 16,17 About 40 years ago, selenium was recognized as essential in human and animal nutrition being proven that its deficiency produces two serious diseases, Keshan and Kashin-Beck illness, affecting in particular areas of China. 17 The first one is related to heart diseases that affect children.…”

Section: Introductionmentioning

confidence: 99%

Novel selenium‐doped hydroxyapatite coatings for biomedical applications

Rodríguez-Valencia

López‐Álvarez

Cochón-Cores

et al. 2012

J Biomedical Materials Res

110

View full text Add to dashboard Cite

Nowadays there is a short-term need of investigating in orthopedic implants with a greater functionality, including an improved osseointegration and also antibacterial properties. The coating of metallic implants with hydroxyapatite (HA) remains to be the main proposal, but superior quality HA coatings with compositions closer to natural bone apatites, including carbonates, trace elements are required. Selenium is an essential nutrient in biological tissues and, at the same time, it also presents antibacterial properties. A pioneering study on the fabrication of selenium-doped carbonated hydroxyapatite (iHA:Se) coatings by Pulsed Laser Deposition (PLD) is presented. Different proportions of selenium were incorporated to obtain the iHA:Se coatings. Their physicochemical characterization, performed by SEM/EDS, FTIR, FT-Raman, Interferometric Profilometry and XPS, revealed typical columnar growth of HA in globular aggregates and the efficient incorporation of selenium into the HA coatings by the, most probably, substitution of SeO(3)(2-) groups in the CO(3)(2-) sites. Biological evaluation illustrated the absence of cytotoxicity when an amount of 0.6 at.% of Se was added to the iHA:Se coatings and excellent proliferation of the MC3T3-E1 preosteoblasts. Antibacterial properties were also proved with the inhibition of P. aeruginosa and S. aureus from establishing bacterial biofilms.

show abstract

The Effect of Age and Gender on 38 Chemical Element Contents in Human Femoral Neck Investigated by Instrumental Neutron Activation Analysis

Cited by 50 publications

References 19 publications

Factors that Affect the Content of Cadmium, Nickel, Copper and Zinc in Tissues of the Knee Joint

Factors that Affect the Content of Cadmium, Nickel, Copper and Zinc in Tissues of the Knee Joint

Comparison of Metal Concentrations in Bones of Long-Living Mammals

Novel selenium‐doped hydroxyapatite coatings for biomedical applications

Contact Info

Product

Resources

About