The Effect of Aluminum Nanoparticles on Vaccine-dosed Rabbits Investigated Using Cyclic Voltammetry

Abstract

This study investigates the effect of aluminum nanoparticles (AL NPs) on vaccines (e.g., poliomyelitis and bacille Calmette-Guérin (BCG) vaccines). Cyclic voltammetry was used to determine the extent of its effect on the blood composition using an in vivo study on blood samples obtained from rabbits injected with poliomyelitic virus and BCG vaccines across a period of four weeks. The oxidation current peaks of the vaccines in the rabbit blood samples were enhanced with increasing doses of AL NPs. AL NPs acted as oxidative reagents to the rabbit blood components.