The effect of an intermediate dose of labetalol on heart rate and blood pressure responses to laryngoscopy and intubation

Effects of stellate ganglion block on cardiovascular reaction and heart rate variability in elderly patients during anesthesia induction and endotracheal intubation

“…Several approaches are used clinically to reduce cardiovascular responses during anesthesia induction and endotracheal intubation. Medicines that regulate the function of the cardiovascular system, such as esmolol, labetalol, nitroglycerin, and clonidine, for example, are widely applied [5][6][7][8]. The use of lidocaine as topical anesthesia for pars laryngeal pharynges has been reported [9], and increasing the dosage of anesthetic medicines to inhibit reactions of the cardiovascular system is a common practice [10].…”

Comparative Study of Attenuation of effects of Intubation on Blood Pressure Using IV Xylocard and IV Beta Blocker (Esmolol)

“…Haranth K.Baba (1974) opined That the E.C.G changes observed at intubation was due to a combination of effects of the inducing agent earlier and the effect or passing end tracheal tube later. [10] Abou-Madi (1977) reported that a dose of 0.75 mg/kg of intravenous lignocaine was insufficient as antiarrhythmic while a dose of 1.5 mg/kg of i.v. lignocaine afforded complete protection against arrhythmias and also tachycardia, is similar to our finding of decreased tachycardia and absence of arrhythmias in group B.…”

Effects of landiolol on QT interval and QT dispersion during induction of anesthesia using computerized measurement

“…They attenuate the unexpected increase in HR. Therefore, β-adrenoceptor antagonists, such as esmolol or labetalol, have been used to prevent hyperdynamic responses induced by laryngoscopy and tracheal intubation [3][4][5][6][7]25]. Landiolol, a newer, ultra-short-acting β 1 -adrenoceptor antagonist, has been proposed as an alternative drug to avoid adverse hemodynamic effects caused by intubation [1,8].…”

“…Many studies have been performed to prevent hyperdynamic responses induced by tracheal intubation [1][2][3][4][5][6][7][8]. Of the various classes of drugs, β-adrenoceptor antagonists have frequently been used to prevent such detrimental events.…”