The Effect of Antipsychotics on Prolactinoma Growth: A Radiological and Serological Analysis
Umar S Durrani,
Satvik Vasireddy,
Maha Z Arshad
et al.
Abstract:Many antipsychotic (AP) medications work by reducing dopamine levels. As hyperdopaminergia is known to cause psychosis, antipsychotics work to relieve these symptoms by antagonizing dopamine receptors and lowering dopamine levels. Dopamine is also a known negative modulator of the prolactin pathway, which allows for drug agents like dopamine agonists (DAs) to be incredibly effective in managing tumors that secrete excess prolactin (prolactinomas). While the effects of DAs on prolactinoma size and growth have b… Show more
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