The effect of application of a Soton ureteroscope on infection after flexible ureteroscopy lithotripsy.

Abstract

Introduction: Postoperative infection is still one of the most common complications following flexible ureteroscopy lithotripsy (FURL). However, whether a combination of negative pressure ureteroscopy (and Soton ureteroscopy) is superior to FURL in lithotripsy with regard to intraoperative pressure and possibly the incidence of postoperative infection remains to be validated. Aim: To explore the effect of a Soton ureteroscope on infection following flexible ureteroscope lithotripsy. Material and methods: Sixty patients with kidney stones were randomly divided equally into study and control groups. The operation duration, stone-free rate, postoperative blood routine, procalcitonin, C-reactive protein, and other data between the two groups were then analysed and compared. Results: There were no statistically significant differences between the study group and the control group regarding the average operation time and the average number of hospitalization days. The mean stone-free rate 1 week after surgery and mean VAS pain score 1 day after surgery for the study group and the control group were 91.3% and 0.27 vs. 76.9% and 0.61, respectively. Notably, the average body temperature after the first day of the operation was 36.4°C in the study group and 36.7°C in the control group. More importantly, concerning postoperative infection index, white blood cells (WBCs), percentage of neutrophils, C-reactive protein, and procalcitonin were all lower in the study group than in the control group. Conclusions: Compared with flexible ureteroscopy alone, combined use of Soton ureteroscopy is associated with fewer substantially infection following lithotripsy.

Single-use flexible ureteroscope provides an alternative treatment for upper urinary calculi: A systematic review and meta-analysis

“…[23] High upper urinary tract pressures make up another notable risk, continuous filling and fluid flushing in the lithotriptic process make the high pressure, leading to possible absorption of bacteria and endotoxin into the bloodstream, increasing the risk of postoperative infection. [24] However, the pressure generated by using the 2 devices has not been definitively confirmed by relevant research, and many other factors like stone type, and operation time may also contribute to the infection rate. Larger prospective human in vivo studies are required to further understand pressure thresholds and clinical sequelae.…”