The Effect of Bacillus Coagulans and Galactomannans on the Quality of Life of Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Clinical Trial

Kazzi, Fay; Daher, Noha; Kray, Genevieve; Zimmerman, Grenith; Scharf, Keith

doi:10.1007/s13126-018-0456-0

Cited by 8 publications

(18 citation statements)

References 28 publications

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“…Out of the 59 studies, 36 studies applied a pre-post design (baseline measurements provided) (Group 1: n = 23 [ 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 ]; Group 2: n = 10 [ 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 ]; Group 3: n = 4 [ 70 , 71 , 72 , 73 ]). Sixteen studies used a cross-sectional design (Group 1: n = 6 [ 74 , 75 , 76 , 77 , 78 , 79 ]; Group 2: n = 10 [ 80 , 81 , 82 , 83 , 84 , 85 , 86 ,…”

Section: Resultsmentioning

confidence: 99%

“…For Groups 1 and 2, outcome results including microbiota diversity and taxonomy changes are available in detail in Supporting Table S2 . The outcomes for Group 3 included clinical, anthropometric and/or metabolic parameters [ 70 , 72 , 73 ] and Quality of Life (QoL) [ 71 ] and are detailed in Supporting Table S3 . Analysis of microbiota samples were completed predominantly via next generation sequencing of 16S rRNA gene amplicons (Group 1: n = 23; Group 2: n = 22; Group 3: n = 1), with largely the hypervariable regions V3 and V4 targeted (detailed across studies below in the risk of bias section and for individual studies in Supporting Table S1 ).…”

Section: Resultsmentioning

confidence: 99%

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Gut Microbiota, Probiotics and Psychological States and Behaviors after Bariatric Surgery—A Systematic Review of Their Interrelation

et al. 2020

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The gastrointestinal (GI) microbiota plays an important role in health and disease, including brain function and behavior. Bariatric surgery (BS) has been reported to result in various changes in the GI microbiota, therefore demanding the investigation of the impact of GI microbiota on treatment success. The goal of this systematic review was to assess the effects of BS on the microbiota composition in humans and other vertebrates, whether probiotics influence postoperative health, and whether microbiota and psychological and behavioral factors interact. A search was conducted using PubMed and Web of Science to find relevant studies with respect to the GI microbiota and probiotics after BS, and later screened for psychological and behavioral parameters. Studies were classified into groups and subgroups to provide a clear overview of the outcomes. Microbiota changes were further assessed for whether they were specific to BS in humans through the comparison to sham operated controls in other vertebrate studies. Changes in alpha diversity appear not to be specific, whereas dissimilarity in overall microbial community structure, and increases in the abundance of the phylum Proteobacteria and Akkermansia spp. within the phylum Verrucomicrobia after surgery were observed in both human and other vertebrates studies and may be specific to BS in humans. Human probiotic studies differed regarding probiotic strains and dosages, however it appeared that probiotic interventions were not superior to a placebo for quality of life scores or weight loss after BS. The relationship between GI microbiota and psychological diseases in this context is unclear due to insufficient available data.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Gut Microbiota, Probiotics and Psychological States and Behaviors after Bariatric Surgery—A Systematic Review of Their Interrelation

et al. 2020

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“…Only one report [22] performed a single-blind trial on patients without blinding the researchers and study personnel; thus, it was considered as "high risk" in performance bias. Two trials conducted by Kazzi [22] and Chen [25] did not specify whether the outcome measurer was blinded and were categorized with an "unclear risk" in detection bias. One trial described patient age, sex, and BMI and lacked baseline comparability [25].…”

Section: Assessment Of Risk Of Bias Figures 2 and 3 Show The Qualitymentioning

confidence: 99%

“…e quality of three studies [19][20][21] was grade A, and probability of bias was low. e remaining three studies [22,25,28] were grade B with a moderate probability of bias.…”

Section: Assessment Of Risk Of Bias Figures 2 and 3 Show The Qualitymentioning

confidence: 99%

“…However, another study [20] showed that administering probiotics does not improve anthropometric measurements in patients following laparoscopic SG. Furthermore, the effects of probiotics on the QoL, vitamin availability, and inflammation remain unclear [19][20][21][22]. An integrative review [23] described the impact of probiotics to reduce the gastrointestinal symptoms in postoperative patients but lacked the use of systematic retrieval methods and quality assessment of the literature.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Microecological Preparations on Obese Patients after Bariatric Surgery: A Systematic Review and Meta‐Analysis

Zhu

Ren

Zang

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Vitamin deficiency, bacterial overgrowth, and gastrointestinal symptoms can be detected in obese patients after bariatric surgery that influences their quality of life (QoL) and weight. It is unclear if microecological preparations benefit obese patients following bariatric surgery. The aim of this study is to investigate the effects of microecological preparations on QoL, excess weight loss (EWL), and levels of vitamin B12 and inflammatory markers. We searched seven databases to identify reports published till December 1, 2019, and included randomized controlled trials investigating the effects of microecological preparations in obese adults undergoing bariatric surgery. The primary outcomes included QoL and EWL, while secondary outcomes comprised serum levels of vitamin B12, interleukin 6, TNF-α, and C-reactive protein (CRP). Study bias was analyzed using the Cochrane risk-of-bias tool. Statistical analyses were performed using Review Manager. The mean difference in outcomes was calculated using standardized mean difference (SMD) with a confidence interval (CI) of 95%. A majority of the studies showed a low or moderate risk of bias. Meta-analysis showed significantly higher levels of vitamin B12 in postoperative patients administered with microecological preparations (SMD = 0.52; 95% CI = 0.08–0.95; P=0.02). There were no significant differences in QoL (SMD = −0.14; 95% CI = −0.45–0.17; P=0.38), EWL (SMD = 0.45; 95% CI = −0.16–1.05; P=0.15), and levels of TNF-α (SMD = −0.29; 95% CI = −0.64–0.05; P=0.09), interleukin 6 (SMD = −0.1; 95% CI = −0.81–0.61; P=0.78]), and CRP (SMD = 0.02; 95% CI = −0.32–0.36; P=0.93). The trials examined indicated that microecological preparations had limited efficacy in improving QoL, EWL, and inflammatory response, but they stimulated the synthesis of vitamin B12. This may help in designing efficient microecological preparations to supplement bariatric surgery in obese individuals.

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Bariatric Surgery and Quality of Life

Ayiomamitis

2018

Hellenic J Surg

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The Effect of Bacillus Coagulans and Galactomannans on the Quality of Life of Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Randomized Controlled Clinical Trial

Cited by 8 publications

References 28 publications

Gut Microbiota, Probiotics and Psychological States and Behaviors after Bariatric Surgery—A Systematic Review of Their Interrelation

Gut Microbiota, Probiotics and Psychological States and Behaviors after Bariatric Surgery—A Systematic Review of Their Interrelation

Effects of Microecological Preparations on Obese Patients after Bariatric Surgery: A Systematic Review and Meta‐Analysis

Bariatric Surgery and Quality of Life

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