The effect of benzo[a]pyrene on the gut microbiota of Nile tilapia (Oreochromis niloticus)

Quintanilla-Mena, Mercedes; Vega-Arreguín, Julio; Río-García, Marcela Del; Patiño-Suárez, V.; Peraza-Echeverría, Santy; Puch-Hau, Carlos

doi:10.1007/s00253-021-11592-5

Cited by 9 publications

(3 citation statements)

References 72 publications

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“…DEPs contain different PAHs, a class of organic compounds well‐known to be toxic, mutagenic, and genotoxic to various life forms (Patel et al, 2020 ; Sun et al, 2021 ). Also, shifts in the microbial gut community due to PAH exposure have been reported in different animals, such as fish, sea cucumbers, or potworms (Enchytraeidae) (DeBofsky et al, 2020 , 2021 ; Ding et al, 2020 ; Quintanilla‐Mena et al, 2021 ; Zhao et al, 2019 ). Therefore, we suspect PAHs to be the leading cause of changes in the bumblebee gut microbiome in our study.…”

Section: Discussionmentioning

confidence: 99%

Diesel exhaust particles alter gut microbiome and gene expression in the bumblebee Bombus terrestris

Seidenath

Weig

Mittereder

et al. 2023

Ecology and Evolution

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Section: Discussionmentioning

confidence: 99%

Diesel exhaust particles alter gut microbiome and gene expression in the bumblebee Bombus terrestris

Seidenath

Weig

Mittereder

et al. 2023

Ecology and Evolution

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“…Benzo[a]pyrene (BaP) is a common polycyclic aromatic compound which is easy to be produced in the processing of petroleum and fatty food. It is a strong carcinogen and has strong immunotoxicity and reproductive toxicity [ 85 , 86 , 87 ]. As the main metabolic organ of BaP intake, the ability of the liver to metabolize BAP is much stronger than that of other organs, so the hepatotoxicity caused by BAP is also stronger than that of other organs [ 88 , 89 , 90 ].…”

Section: The Role Of Autophagy and Pyroptosis In Liver Disordersmentioning

confidence: 99%

The Role of Autophagy and Pyroptosis in Liver Disorders

Zhao

Liu

Yang

et al. 2022

IJMS

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Pyroptosis is a programmed cell death caused by inflammasomes, which can detect cell cytosolic contamination or disturbance. In pyroptosis, caspase-1 or caspase-11/4/5 is activated, cleaving gasdermin D to separate its N-terminal pore-forming domain (PFD). The oligomerization of PFD forms macropores in the membrane, resulting in swelling and membrane rupture. According to the different mechanisms, pyroptosis can be divided into three types: canonical pathway-mediated pyroptosis, non-canonical pathway-mediated pyroptosis, and caspase-3-induced pyroptosis. Pyroptosis has been reported to play an important role in many tissues and organs, including the liver. Autophagy is a highly conserved process of the eukaryotic cell cycle. It plays an important role in cell survival and maintenance by degrading organelles, proteins and macromolecules in the cytoplasm. Therefore, the dysfunction of this process is involved in a variety of pathological processes. In recent years, autophagy and pyroptosis and their interactions have been proven to play an important role in various physiological and pathological processes, and have gradually attracted more and more attention to become a research hotspot. Therefore, this review summarized the role of autophagy and pyroptosis in liver disorders, and analyzed the related mechanism to provide a basis for future research.

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“…Many studies have reported that different degrees of heavy metal pollution have been detected within seafood in the coastal areas of China (Liu et al, 2018;Milenkovic et al, 2019;Hossain, 2020;Liu et al, 2020a;Ngoc et al, 2020;Pandion et al, 2022). Benzo[a]pyrene (B[a]P) is a common persistent organic pollutant (POP) that is widely found in aquaculture environments and has stable properties, strong toxicity, and carcinogenic effects (Quintanilla-Mena et al, 2021;Ju et al, 2022). Other studies have revealed that shellfish biomagnifies B [a]P; and high B[a]P content has been detected in various shellfish samples (Qu et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

Bioaccumulation of contaminants in wild seahorses collected from coastal China

et al. 2022

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Eighty-four wild seahorses, including three of China’s dominant species, were collected from seven coastal provinces to evaluate their common contaminant contents. Heavy metals (including Cu, Pb, Cd, Cr, and Hg), Benzo(a)pyrene (B[a]P), and microplastics were detected in the collected seahorses. The results indicate that considerable contamination variations are present in seahorses from different regions and species. Elevated concentrations of Cu and Cr, compared to other heavy metals, were observed in most sampled locations. In addition, B[a]P concentrations were far greater in Hippocampus mohnikei and H.trimaculatus compared with H.kelloggi (P < 0.05). Substantial changes in microplastic concentrations were also observed in seahorses from different locations, and significant differences were observed between sampled species (P < 0.05). Further, a correlation analysis obtained strong correlations among four heavy metals (Cu, Pb, Cd, and Cr), except Hg. A significant correlation was identified between B[a]P and microplastics (P < 0.01), suggesting potential synergistic effects between these two contaminants. In brief, this study indicates that wild seahorse populations are experiencing environmental pollution.

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The effect of benzo[a]pyrene on the gut microbiota of Nile tilapia (Oreochromis niloticus)

Cited by 9 publications

References 72 publications

Diesel exhaust particles alter gut microbiome and gene expression in the bumblebee Bombus terrestris

Diesel exhaust particles alter gut microbiome and gene expression in the bumblebee Bombus terrestris

The Role of Autophagy and Pyroptosis in Liver Disorders

Bioaccumulation of contaminants in wild seahorses collected from coastal China

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