The Effect of Beta-blocker Assessed by Repeat Head-up Tilt Test in Adults with Vasovagal Syncope or Presyncope

Background and Objectives Neurocardiogenic syncope is believed to be caused by a transient imbalance of autonomic nervous system. Actually, there were significant differences in heart rate variability HRV indices during head-up tilt test between patients with neurocardiogenic syncope and normal controls. But there was no definite evidence for it during daily activity. So, we tried to evaluate HRV during daily activity with 24-hour ambu-latory electrocardiography monitoring. Materials and Methods 27 patients with neurocardiogenic syncope or presyncope mean age 45 3 and 25 normal volunteers mean age 47 2 comparable for age and sex underwent 24-hour ambulatory electrocardiography. Head-up tilt test was used to diagnose neurocardiogenic syncope or presyncope in patients group. HRV was analysed over the whole 24 hours, using time and frequency domain parameters. Student's t-test was applied. Results There were no significant differences in HRV measures between two groups, over 24-hour period and day-time and night-time period. But the hourly HRV measures showed a transient decrease of LF, LFnorm and LF HF ratio in patients group compared to normal control group. Conclusions These results indicate that patients with neurocardiogenic syncope or presyncope suffer from temporarily decreased sympathetic tone with normal parasympathetic tone. So, transient additive change of autono-mic nervous tone may cause syncope or presyncope in these patients. Korean Circulation J 2000 ; 30 6 : 716-723

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Usefulness of tilt training in patients with neurocardiogenic syncope

Choe

Kim

Hong

et al. 2001

Korean Circ J

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The Effect of Beta-blocker Assessed by Repeat Head-up Tilt Test in Adults with Vasovagal Syncope or Presyncope

Cited by 3 publications

References 21 publications

Long-term Follow-up in Patients with Neurocardiogenic Syncope with or without Therapy

Long-term Follow-up in Patients with Neurocardiogenic Syncope with or without Therapy

Heart Rate Variability in Patients with Neurocardiogenic Syncope or Presyncope

Usefulness of tilt training in patients with neurocardiogenic syncope

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