The effect of biofilm formation on the outcome therapy of diabetic foot infections (DFIs) patients in the outpatient clinic and inpatient ward of Dr Sardjito General Hospital Yogyakarta

Abstract

Introduction: Diabetes is a non-communicable disease with incidence rate of about 1.5 – 2.3% per annum with the most complication is Diabetic Foot Infections (DFIs). Objective: This research was conducted to describe the bacteria responsible for biofilm formation and its ability to cause DFIs in biofilm formation at Dr. Sardjito General Hospital as well as the therapy outcome. Methods: This research was conducted from September to November 2017. Specimens of samples were obtained from wound swabs of DFIs patients who met the inclusion and exclusion criteria (31 outpatients and 15 inpatients), and were then tested for culture and sensitivity and their ability to form biofilms. Results: The DFIs with the biofilm-producing bacteria (weak to moderate) have a different outcome compared to DFIs patients without biofilms.