2024
DOI: 10.5115/acb.23.256
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The effect of biological mechanisms of melatonin on the proliferation of spermatogonial stem cells: a systematic review

Shadan Navid,
Zahra Saadatian,
Ali Talebi
et al.

Abstract: In the last decade, melatonin has gained recognition as a potent scavenger and an effective antioxidant capable of neutralizing free radicals, including reactive oxygen species. Additionally, it exhibits anti-apoptotic properties. In this review, we will examine a compilation of articles that explore the cellular signaling function of melatonin on spermatogonial stem cells (SSCs) and adjacent cells such as Sertoli and Leydig cells. These cells play a crucial role in the proliferation of SSCs both i… Show more

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