The effect of biologically active substances of thyme (Thymus vulgaris L.) on the growth of yeast cells

Abstract

Prolongation of life expectancy and improvement of phenotypes directly related to the aging process have been the objects of many studies. Some of the known methods of increasing life expectancy, including dietary restrictions and genetic manipulation, are difficult to apply to all people, and their side effects are difficult to predict. It is for this reason that it becomes important to find those biologically active compounds that can act as anti-aging agents or can induce prolongation of life due to various metabolic processes inside the cell. The medicinal plant SFO thyme (Thymus vulgaris L.) is a source of many active compounds that can affect life expectancy. The present study was conducted to evaluate the effect of biologically active compounds of the extract of the callus culture of Thymus vulgaris L., dried by spray drying at different temperature conditions (60 ℃, 90 ℃, 120 ℃), on the growth of the experimental model Saccharomyces cerevisiae Y-564. Anti-aging effect of dry extract of callus culture Thymus vulgaris L. with concentrations of 0.25 mg/ml, 0.50 mg/ml and 1.00 mg/ml on a model yeast organism, the yeast cells were evaluated by increasing the biomass of yeast cells. The results of the studies showed that the best variant of the effect of the growth properties of the biomass of the yeast suspension S. cerevisiae Y-564 showed an extract of the callus culture Thymus vulgaris L., dried at a temperature of 90 ℃, with a concentration of 0.50 mg / ml. It was under such conditions that a stimulating increase in the biomass of the test culture was observed. These results of this study provide new insights into the mechanisms by which biologically active compounds extracted from the callus culture of Thymus vulgaris L. can slow down the aging process.